γ-Glutamyl-Transpeptidase-Resistant Glutathione Analog Attenuates Progression of Alzheimer’s Disease-like Pathology and Neurodegeneration in a Mouse Model
Oxidative stress in Alzheimer’s disease (AD) is mediated, in part, by the loss of glutathione (GSH). Previous studies show that γ-glutamyl transpeptidase (GGT)-resistant GSH analog, Ψ-GSH, improves brain GSH levels, reduces oxidative stress markers in brains of APP/PS1 transgenic mice, a mouse model...
Guardado en:
Autores principales: | Ye In Christopher Kwon, Wei Xie, Haizhou Zhu, Jiashu Xie, Keaton Shinn, Nicholas Juckel, Robert Vince, Swati S. More, Michael K. Lee |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2cdccac0ab3f4519869f07119d79c7b7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Glia maturation factor-β: a potential therapeutic target in neurodegeneration and neuroinflammation
por: Fan J, et al.
Publicado: (2018) -
Fluorescent serum and urinary advanced glycoxidation end-products in non- diabetic subjects
por: DE LA MAZA,MP, et al.
Publicado: (2007) -
Natural Dietary Supplement, Carvacrol, Alleviates LPS-Induced Oxidative Stress, Neurodegeneration, and Depressive-Like Behaviors via the Nrf2/HO-1 Pathway
por: Naeem K, et al.
Publicado: (2021) -
Soluble receptor for advanced glycation end products in critically ill patients and its associations with other clinical markers and 28-day mortality
por: Cheng YZ, et al.
Publicado: (2014) -
Methylglyoxal Detoxification Revisited: Role of Glutathione Transferase in Model Cyanobacterium <italic toggle="yes">Synechocystis</italic> sp. Strain PCC 6803
por: Xavier Kammerscheit, et al.
Publicado: (2020)