Fetal Surveillance in Pregnancies with Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune condition, that commonly impacts adult women of reproductive age. Myasthenia gravis in pregnancy is rare, but the incidence is higher in different geographical areas. Pregnancies in mothers with MG can have an unfortunate outcome. Acetylcholine receptor antibo...

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Autores principales:	Brîndușa Ana Cimpoca-Raptis, Anca Marina Ciobanu, Nicolae Gica, Gheorghe Peltecu, Dan Mitrea, Anca Maria Panaitescu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	myasthenia gravis pregnancy arthrogryposis transient neonatal myasthenia gravis Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/2ceae6e0f8784196aa33ca2fb697ea19
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id	oai:doaj.org-article:2ceae6e0f8784196aa33ca2fb697ea19
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spelling	oai:doaj.org-article:2ceae6e0f8784196aa33ca2fb697ea192021-11-25T18:19:10ZFetal Surveillance in Pregnancies with Myasthenia Gravis10.3390/medicina571112771648-91441010-660Xhttps://doaj.org/article/2ceae6e0f8784196aa33ca2fb697ea192021-11-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1277https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144Myasthenia gravis (MG) is an autoimmune condition, that commonly impacts adult women of reproductive age. Myasthenia gravis in pregnancy is rare, but the incidence is higher in different geographical areas. Pregnancies in mothers with MG can have an unfortunate outcome. Acetylcholine receptor antibodies may pass into the fetal circulation and can affect the fetal neuromuscular junction, generating transient MG or even fetal arthrogryposis. The 2016 and 2021 International Consensus Guidance for Management of Myasthenia Gravis issued by Myasthenia Gravis Foundation of America is lacking in recommendation for fetal surveillance for pregnancies in women with MG. The aim of this paper is to highlight fetal and neonatal complications in mothers with MG and to offer antenatal care insights. Close maternal and pregnancy monitoring can improve pregnancy outcome. Patients with MG should be encouraged to conceive, to avoid triggers for exacerbations of the disease during pregnancy and a multidisciplinary team should be established to ensure the optimal support and therapy.Brîndușa Ana Cimpoca-RaptisAnca Marina CiobanuNicolae GicaGheorghe PeltecuDan MitreaAnca Maria PanaitescuMDPI AGarticlemyasthenia gravispregnancyarthrogryposistransient neonatal myasthenia gravisMedicine (General)R5-920ENMedicina, Vol 57, Iss 1277, p 1277 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	myasthenia gravis pregnancy arthrogryposis transient neonatal myasthenia gravis Medicine (General) R5-920
spellingShingle	myasthenia gravis pregnancy arthrogryposis transient neonatal myasthenia gravis Medicine (General) R5-920 Brîndușa Ana Cimpoca-Raptis Anca Marina Ciobanu Nicolae Gica Gheorghe Peltecu Dan Mitrea Anca Maria Panaitescu Fetal Surveillance in Pregnancies with Myasthenia Gravis
description	Myasthenia gravis (MG) is an autoimmune condition, that commonly impacts adult women of reproductive age. Myasthenia gravis in pregnancy is rare, but the incidence is higher in different geographical areas. Pregnancies in mothers with MG can have an unfortunate outcome. Acetylcholine receptor antibodies may pass into the fetal circulation and can affect the fetal neuromuscular junction, generating transient MG or even fetal arthrogryposis. The 2016 and 2021 International Consensus Guidance for Management of Myasthenia Gravis issued by Myasthenia Gravis Foundation of America is lacking in recommendation for fetal surveillance for pregnancies in women with MG. The aim of this paper is to highlight fetal and neonatal complications in mothers with MG and to offer antenatal care insights. Close maternal and pregnancy monitoring can improve pregnancy outcome. Patients with MG should be encouraged to conceive, to avoid triggers for exacerbations of the disease during pregnancy and a multidisciplinary team should be established to ensure the optimal support and therapy.
format	article
author	Brîndușa Ana Cimpoca-Raptis Anca Marina Ciobanu Nicolae Gica Gheorghe Peltecu Dan Mitrea Anca Maria Panaitescu
author_facet	Brîndușa Ana Cimpoca-Raptis Anca Marina Ciobanu Nicolae Gica Gheorghe Peltecu Dan Mitrea Anca Maria Panaitescu
author_sort	Brîndușa Ana Cimpoca-Raptis
title	Fetal Surveillance in Pregnancies with Myasthenia Gravis
title_short	Fetal Surveillance in Pregnancies with Myasthenia Gravis
title_full	Fetal Surveillance in Pregnancies with Myasthenia Gravis
title_fullStr	Fetal Surveillance in Pregnancies with Myasthenia Gravis
title_full_unstemmed	Fetal Surveillance in Pregnancies with Myasthenia Gravis
title_sort	fetal surveillance in pregnancies with myasthenia gravis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/2ceae6e0f8784196aa33ca2fb697ea19
work_keys_str_mv	AT brindusaanacimpocaraptis fetalsurveillanceinpregnancieswithmyastheniagravis AT ancamarinaciobanu fetalsurveillanceinpregnancieswithmyastheniagravis AT nicolaegica fetalsurveillanceinpregnancieswithmyastheniagravis AT gheorghepeltecu fetalsurveillanceinpregnancieswithmyastheniagravis AT danmitrea fetalsurveillanceinpregnancieswithmyastheniagravis AT ancamariapanaitescu fetalsurveillanceinpregnancieswithmyastheniagravis
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Fetal Surveillance in Pregnancies with Myasthenia Gravis

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