Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses

Salt levels in culture affect the polarisation of Th17 cells, which normally protect the host from fungal and bacterial infections. Here, the authors study patients with salt-losing tubulopathies (SLT) to find that, while Th17 immunity is dampened in SLT patients, their Th17-inducing signaling pathw...

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Autores principales: Rhys D. R. Evans, Marilina Antonelou, Sanchutha Sathiananthamoorthy, Marilena Rega, Scott Henderson, Lourdes Ceron-Gutierrez, Gabriela Barcenas-Morales, Christoph A. Müller, Rainer Doffinger, Stephen B. Walsh, Alan D. Salama
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2cec9c8266184037b9f92780094ab2b6
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