Dimensionality controls cytoskeleton assembly and metabolism of fibroblast cells in response to rigidity and shape.
<h4>Background</h4>Various physical parameters, including substrate rigidity, size of adhesive islands and micro-and nano-topographies, have been shown to differentially regulate cell fate in two-dimensional (2-D) cell cultures. Cells anchored in a three-dimensional (3-D) microenvironmen...
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Main Authors: | Mirjam Ochsner, Marcus Textor, Viola Vogel, Michael L Smith |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/2cee3a338a074578bccd98b28edaeef6 |
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