Statins and diabetes: focus on pitavastatin

In this review, the focus is to investigate the effects of long-term statin therapy on glucose metabolism. The author analyzed the evidences of randomized clinical trials, meta-analyses, and experimental studies indicating the diabetogenic effect of the most of statins. Possible mechanisms of influe...

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Autor principal:	Soreiia A. Urazgildeeva
Formato:	article
Lenguaje:	EN RU
Publicado:	Concilium Medicum 2020
Materias:	diabetes mellitus lipid-lowering therapy statins atorvastatin rosuvastatin pitavastatin Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/2cf24e86d6744d7c939504863574c218
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id	oai:doaj.org-article:2cf24e86d6744d7c939504863574c218
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spelling	oai:doaj.org-article:2cf24e86d6744d7c939504863574c2182021-12-01T22:07:01ZStatins and diabetes: focus on pitavastatin2221-71852658-570710.26442/22217185.2020.2.200226https://doaj.org/article/2cf24e86d6744d7c939504863574c2182020-09-01T00:00:00Zhttps://cardiosomatics.orscience.ru/2221-7185/article/viewFile/46030/31034https://doaj.org/toc/2221-7185https://doaj.org/toc/2658-5707In this review, the focus is to investigate the effects of long-term statin therapy on glucose metabolism. The author analyzed the evidences of randomized clinical trials, meta-analyses, and experimental studies indicating the diabetogenic effect of the most of statins. Possible mechanisms of influence of statins on carbohydrate metabolism are presented. Particular attention is paid to the place of pitavastatin, due to its low diabetogenicity and minimal risk of drug interactions, as well as the need of taking into consideration the risk factors of diabetes and the preventive measures in patients receiving statin therapy.Soreiia A. UrazgildeevaConcilium Medicumarticlediabetes mellituslipid-lowering therapystatinsatorvastatinrosuvastatinpitavastatinDiseases of the circulatory (Cardiovascular) systemRC666-701Diseases of the endocrine glands. Clinical endocrinologyRC648-665ENRUКардиоСоматика, Vol 11, Iss 2, Pp 40-49 (2020)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus lipid-lowering therapy statins atorvastatin rosuvastatin pitavastatin Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	diabetes mellitus lipid-lowering therapy statins atorvastatin rosuvastatin pitavastatin Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665 Soreiia A. Urazgildeeva Statins and diabetes: focus on pitavastatin
description	In this review, the focus is to investigate the effects of long-term statin therapy on glucose metabolism. The author analyzed the evidences of randomized clinical trials, meta-analyses, and experimental studies indicating the diabetogenic effect of the most of statins. Possible mechanisms of influence of statins on carbohydrate metabolism are presented. Particular attention is paid to the place of pitavastatin, due to its low diabetogenicity and minimal risk of drug interactions, as well as the need of taking into consideration the risk factors of diabetes and the preventive measures in patients receiving statin therapy.
format	article
author	Soreiia A. Urazgildeeva
author_facet	Soreiia A. Urazgildeeva
author_sort	Soreiia A. Urazgildeeva
title	Statins and diabetes: focus on pitavastatin
title_short	Statins and diabetes: focus on pitavastatin
title_full	Statins and diabetes: focus on pitavastatin
title_fullStr	Statins and diabetes: focus on pitavastatin
title_full_unstemmed	Statins and diabetes: focus on pitavastatin
title_sort	statins and diabetes: focus on pitavastatin
publisher	Concilium Medicum
publishDate	2020
url	https://doaj.org/article/2cf24e86d6744d7c939504863574c218
work_keys_str_mv	AT soreiiaaurazgildeeva statinsanddiabetesfocusonpitavastatin
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Statins and diabetes: focus on pitavastatin

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