Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.

Statistical image analysis of an ensemble of digital images of histological samples is performed as an auxiliary investigation a result of the recently proposed method of articular cartilage repair utilizing growth plate chondrocytes in a skeleton animal model. A fixed-shift model of maximal likelih...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ryszard Tomaszewski, Jerzy Dajka
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2cf35922bb9742ab85124e91ceaf0044
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2cf35922bb9742ab85124e91ceaf0044
record_format	dspace
spelling	oai:doaj.org-article:2cf35922bb9742ab85124e91ceaf00442021-12-02T20:07:07ZStatistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.1932-620310.1371/journal.pone.0252505https://doaj.org/article/2cf35922bb9742ab85124e91ceaf00442021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0252505https://doaj.org/toc/1932-6203Statistical image analysis of an ensemble of digital images of histological samples is performed as an auxiliary investigation a result of the recently proposed method of articular cartilage repair utilizing growth plate chondrocytes in a skeleton animal model. A fixed-shift model of maximal likelihood estimates of image histograms applied for monochromatic (grayscale) images or their RGB components confirms the statistically significant effect of the previously proposed medical treatment. The type of staining used to prepare images of histological samples is related to the visibility of the effectiveness of medical treatment. Hellinger distance of escort distributions for maximal likelihood estimates of image histograms of medically treated and control samples is investigated to identify grayscale (or RGB) intensities responsible for statistically significant difference of the estimates. A difference of Shannon entropy quantifying informational content of the histograms allows one to identify staining and image colors which are most suitable to visualize cluster formation typical for articular cartilage repair processes.Ryszard TomaszewskiJerzy DajkaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0252505 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ryszard Tomaszewski Jerzy Dajka Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.
description	Statistical image analysis of an ensemble of digital images of histological samples is performed as an auxiliary investigation a result of the recently proposed method of articular cartilage repair utilizing growth plate chondrocytes in a skeleton animal model. A fixed-shift model of maximal likelihood estimates of image histograms applied for monochromatic (grayscale) images or their RGB components confirms the statistically significant effect of the previously proposed medical treatment. The type of staining used to prepare images of histological samples is related to the visibility of the effectiveness of medical treatment. Hellinger distance of escort distributions for maximal likelihood estimates of image histograms of medically treated and control samples is investigated to identify grayscale (or RGB) intensities responsible for statistically significant difference of the estimates. A difference of Shannon entropy quantifying informational content of the histograms allows one to identify staining and image colors which are most suitable to visualize cluster formation typical for articular cartilage repair processes.
format	article
author	Ryszard Tomaszewski Jerzy Dajka
author_facet	Ryszard Tomaszewski Jerzy Dajka
author_sort	Ryszard Tomaszewski
title	Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.
title_short	Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.
title_full	Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.
title_fullStr	Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.
title_full_unstemmed	Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.
title_sort	statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/2cf35922bb9742ab85124e91ceaf0044
work_keys_str_mv	AT ryszardtomaszewski statisticalimageanalysisandescorthistogramsincharacterizationofarticularcartilagerepairinaskeletonanimalmodel AT jerzydajka statisticalimageanalysisandescorthistogramsincharacterizationofarticularcartilagerepairinaskeletonanimalmodel
_version_	1718375292868755456

Statistical image analysis and escort histograms in characterization of articular cartilage repair in a skeleton animal model.

Ejemplares similares