Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations
Oesophageal squamous-cell carcinoma (ESCC) is a leading cause of cancer death, and half of ESCC cases occur in China. Here, the authors provide an in depth genomic landscape for this disease and identify specific mutation signatures—one of which is linked to alcohol intake.
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Nature Portfolio
2017
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oai:doaj.org-article:2cf7960033664617b9f8849537a0a6b62021-12-02T15:38:53ZGenomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations10.1038/ncomms152902041-1723https://doaj.org/article/2cf7960033664617b9f8849537a0a6b62017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15290https://doaj.org/toc/2041-1723Oesophageal squamous-cell carcinoma (ESCC) is a leading cause of cancer death, and half of ESCC cases occur in China. Here, the authors provide an in depth genomic landscape for this disease and identify specific mutation signatures—one of which is linked to alcohol intake.Jiang ChangWenle TanZhiqiang LingRuibin XiMingming ShaoMengjie ChenYingying LuoYanjie ZhaoYun LiuXiancong HuangYuchao XiaJinlin HuJoel S. ParkerDavid MarronQionghua CuiLinna PengJiahui ChuHongmin LiZhongli DuYaling HanWen TanZhihua LiuQimin ZhanYun LiWeimin MaoChen WuDongxin LinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jiang Chang Wenle Tan Zhiqiang Ling Ruibin Xi Mingming Shao Mengjie Chen Yingying Luo Yanjie Zhao Yun Liu Xiancong Huang Yuchao Xia Jinlin Hu Joel S. Parker David Marron Qionghua Cui Linna Peng Jiahui Chu Hongmin Li Zhongli Du Yaling Han Wen Tan Zhihua Liu Qimin Zhan Yun Li Weimin Mao Chen Wu Dongxin Lin Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations |
| description |
Oesophageal squamous-cell carcinoma (ESCC) is a leading cause of cancer death, and half of ESCC cases occur in China. Here, the authors provide an in depth genomic landscape for this disease and identify specific mutation signatures—one of which is linked to alcohol intake. |
| format |
article |
| author |
Jiang Chang Wenle Tan Zhiqiang Ling Ruibin Xi Mingming Shao Mengjie Chen Yingying Luo Yanjie Zhao Yun Liu Xiancong Huang Yuchao Xia Jinlin Hu Joel S. Parker David Marron Qionghua Cui Linna Peng Jiahui Chu Hongmin Li Zhongli Du Yaling Han Wen Tan Zhihua Liu Qimin Zhan Yun Li Weimin Mao Chen Wu Dongxin Lin |
| author_facet |
Jiang Chang Wenle Tan Zhiqiang Ling Ruibin Xi Mingming Shao Mengjie Chen Yingying Luo Yanjie Zhao Yun Liu Xiancong Huang Yuchao Xia Jinlin Hu Joel S. Parker David Marron Qionghua Cui Linna Peng Jiahui Chu Hongmin Li Zhongli Du Yaling Han Wen Tan Zhihua Liu Qimin Zhan Yun Li Weimin Mao Chen Wu Dongxin Lin |
| author_sort |
Jiang Chang |
| title |
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations |
| title_short |
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations |
| title_full |
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations |
| title_fullStr |
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations |
| title_full_unstemmed |
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations |
| title_sort |
genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/2cf7960033664617b9f8849537a0a6b6 |
| work_keys_str_mv |
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