Living functional hydrogels generated by bioorthogonal cross-linking reactions of azide-modified cells with alkyne-modified polymers

Cells are often passively encapsulated in hydrogels for a wide range of applications. Here, the authors report on a method of incorporating the cells into the hydrogel using bioorthogonal click reactions to link azide-modified cells with biocompatible polymers to create cell-based materials.

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Detalles Bibliográficos
Autores principales: Koji Nagahama, Yuuka Kimura, Ayaka Takemoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
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Acceso en línea:https://doaj.org/article/2cfd3d3c2b024e1ca5b20f643a7bddd4
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Descripción
Sumario:Cells are often passively encapsulated in hydrogels for a wide range of applications. Here, the authors report on a method of incorporating the cells into the hydrogel using bioorthogonal click reactions to link azide-modified cells with biocompatible polymers to create cell-based materials.