The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor

The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor

Summary: The densely glycosylated spike (S) protein highly exposed on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) surface mediates host cell entry by binding to the receptor angiotensin-converting enzyme 2 (ACE2). However, the role of glycosylation has not been fully understood. In...

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Autores principales: Chuncui Huang, Zeshun Tan, Keli Zhao, Wenjun Zou, Hui Wang, Huanyu Gao, Shiwei Sun, Dongbo Bu, Wengang Chai, Yan Li
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Protein
Virology
Structural biology
Computer simulation
Science
Q
Acceso en línea:https://doaj.org/article/2d0562f6489549838ba1b3d9e2be89f3
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