Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood

Abstract High temperature requirement factor A3 (HtrA3), a member of the HtrA protease family, is highly expressed in the developing placenta, including the maternal decidual cells in both mice and humans. In this study we deleted the HtrA3 gene in the mouse and crossed females carrying zero, one, o...

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Autores principales: Ying Li, Lois A. Salamonsen, Jonathan Hyett, Fabricio da Silva Costa, Guiying Nie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2d0d394657c5485fa77aa96a33501d1e
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