Design, synthesis and docking studies of novel thiazole derivatives incorporating pyridine moiety and assessment as antimicrobial agents
Abstract A novel series of substituted 4,6-dimethyl-2-oxo-1-(thiazol-2-ylamino)-1,2-dihydropyridine-3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield from the reaction of 1-(3-cyano-4,6-dimethyl-2-oxopyridin-1(2H)-yl)thiourea with 2-oxo-N'-arylpropaneh...
Guardado en:
Autores principales: | Rizk E. Khidre, Ibrahim Ali M. Radini |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2d1058b6cf834d6eb481127343b09af4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Design, synthesis of new novel quinoxalin-2(1H)-one derivatives incorporating hydrazone, hydrazine, and pyrazole moieties as antimicrobial potential with in-silico ADME and molecular docking simulation
por: Ahmed Ragab, et al.
Publicado: (2022) -
Design, synthesis, and molecular docking of cysteine-based sulphonamide derivatives as antimicrobial agents
por: Melford C Egbujor, et al.
Publicado: (2022) -
Novel colorimetric chemosensors containing pyridine moiety for detection of some cations in water and crops samples: Design, synthesis, and evaluation
por: Ayman M. Algohary, et al.
Publicado: (2021) -
Thiazole, triazole, thio- and semicarbazone derivatives - Promising moieties for drug development for the treatment of tuberculosis
por: Cauê Benito Scarim, et al.
Publicado: (2021) -
Design, synthesis, and biological activities of novel thiophene, pyrimidine, pyrazole, pyridine, coumarin and isoxazole: Dydrogesterone derivatives as antitumor agents
por: El-Sharkawy Karam A., et al.
Publicado: (2021)