Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response.

Erythropoiesis maintains a stable hematocrit and tissue oxygenation in the basal state, while mounting a stress response that accelerates red cell production in anemia, blood loss or high altitude. Thus, tissue hypoxia increases secretion of the hormone erythropoietin (Epo), stimulating an increase...

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Autores principales: Miroslav Koulnis, Ying Liu, Kelly Hallstrom, Merav Socolovsky
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/2d1e88dd443f4927bf52770e7d30e2f2
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