Bringing biocatalytic deuteration into the toolbox of asymmetric isotopic labelling techniques

Deuterated chemicals are widely exploited in analytical chemistry and increasingly in the synthesis of pharmaceutical compounds. Here, the authors developed a mild biocatalytic method for the selective asymmetric reductive deuteration of organic compounds, by using H2 and 2H2O to generate 2H-NADH....

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Bibliographic Details
Main Authors: J. S. Rowbotham, M. A. Ramirez, O. Lenz, H. A. Reeve, K. A. Vincent
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
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Online Access:https://doaj.org/article/2d3006b0e3ac453589d1a5b6bb9c396e
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