Charting differentially methylated regions in cancer with Rocker-meth

Matteo Benelli et al. present Rocker-meth, a new Hidden Markov Model (HMM)-based method, to robustly identify differentially methylated regions (DMRs). They use Rocker-meth to analyse more than 6000 methylation profiles across 14 cancer types, providing a catalog of tumor-specific and shared DMRs.

Saved in:
Bibliographic Details
Main Authors: Matteo Benelli, Gian Marco Franceschini, Alberto Magi, Dario Romagnoli, Chiara Biagioni, Ilenia Migliaccio, Luca Malorni, Francesca Demichelis
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Online Access:https://doaj.org/article/2d3834fd736a4fd896630a6f3d833ab9
Tags: Add Tag
No Tags, Be the first to tag this record!