Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes

Amrit Pokharel,1 Gauri Shankar Shrestha,2 Jyoti Baba Shrestha2 1Department of Ophthalmology, Kathmandu Medical College Teaching Hospital, 2B P Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Kathmandu, Nepal Purpose: To record the normative values for macular thickness and macu...

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Autores principales:	Pokharel A, Shrestha GS, Shrestha JB
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	macular thickness macular volume optical coherence tomography Nepal Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/2d3a9a6b0fbb46fe8f6cdc789a6e1cc4
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spelling	oai:doaj.org-article:2d3a9a6b0fbb46fe8f6cdc789a6e1cc42021-12-02T05:02:55ZMacular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes1177-5483https://doaj.org/article/2d3a9a6b0fbb46fe8f6cdc789a6e1cc42016-03-01T00:00:00Zhttps://www.dovepress.com/macular-thickness-and-macular-volume-measurements-using-spectral-domai-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Amrit Pokharel,1 Gauri Shankar Shrestha,2 Jyoti Baba Shrestha2 1Department of Ophthalmology, Kathmandu Medical College Teaching Hospital, 2B P Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Kathmandu, Nepal Purpose: To record the normative values for macular thickness and macular volume in normal Nepalese eyes. Methods: In all, 126 eyes of 63 emmetropic subjects (mean age: 21.17±6.76 years; range: 10–37 years) were assessed for macular thickness and macular volume, using spectral domain-optical coherence tomography over 6×6 mm2 in the posterior pole. A fast macular thickness protocol was employed. Statistics such as the mean, median, standard deviation, percentiles, and range were used, while a P-value was set at 0.05 to test significance. Results: Average macular thickness and total macular volume were larger in males compared to females. With each year of increasing age, these variables decreased by 0.556 µm and 0.0156 mm3 for average macular thickness and total macular volume, respectively. The macular thickness was greatest in the inner superior section and lowest at the center of the fovea. The volume was greatest in the outer nasal section and thinnest in the fovea. The central subfield thickness (r=-0.243, P=0.055) and foveal volume (r=0.216, P=0.09) did not correlate with age. Conclusion: Males and females differ significantly with regard to macular thickness and macular volume measurements. Reports by other studies that the increase in axial length reduced thickness and volume, were negated by this study which found a positive correlation among axial length, thickness, and volume. Keywords: macular thickness, macular volume, optical coherence tomography, NepalPokharel AShrestha GSShrestha JBDove Medical Pressarticlemacular thicknessmacular volumeoptical coherence tomographyNepalOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 511-519 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	macular thickness macular volume optical coherence tomography Nepal Ophthalmology RE1-994
spellingShingle	macular thickness macular volume optical coherence tomography Nepal Ophthalmology RE1-994 Pokharel A Shrestha GS Shrestha JB Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes
description	Amrit Pokharel,1 Gauri Shankar Shrestha,2 Jyoti Baba Shrestha2 1Department of Ophthalmology, Kathmandu Medical College Teaching Hospital, 2B P Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Kathmandu, Nepal Purpose: To record the normative values for macular thickness and macular volume in normal Nepalese eyes. Methods: In all, 126 eyes of 63 emmetropic subjects (mean age: 21.17±6.76 years; range: 10–37 years) were assessed for macular thickness and macular volume, using spectral domain-optical coherence tomography over 6×6 mm2 in the posterior pole. A fast macular thickness protocol was employed. Statistics such as the mean, median, standard deviation, percentiles, and range were used, while a P-value was set at 0.05 to test significance. Results: Average macular thickness and total macular volume were larger in males compared to females. With each year of increasing age, these variables decreased by 0.556 µm and 0.0156 mm3 for average macular thickness and total macular volume, respectively. The macular thickness was greatest in the inner superior section and lowest at the center of the fovea. The volume was greatest in the outer nasal section and thinnest in the fovea. The central subfield thickness (r=-0.243, P=0.055) and foveal volume (r=0.216, P=0.09) did not correlate with age. Conclusion: Males and females differ significantly with regard to macular thickness and macular volume measurements. Reports by other studies that the increase in axial length reduced thickness and volume, were negated by this study which found a positive correlation among axial length, thickness, and volume. Keywords: macular thickness, macular volume, optical coherence tomography, Nepal
format	article
author	Pokharel A Shrestha GS Shrestha JB
author_facet	Pokharel A Shrestha GS Shrestha JB
author_sort	Pokharel A
title	Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes
title_short	Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes
title_full	Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes
title_fullStr	Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes
title_full_unstemmed	Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes
title_sort	macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal nepalese eyes
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/2d3a9a6b0fbb46fe8f6cdc789a6e1cc4
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Macular thickness and macular volume measurements using spectral domain optical coherence tomography in normal Nepalese eyes

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