A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
Here the authors describe a simple reverse genetics method that relies on overlapping cDNA fragments for generation of positive-strand viruses including SARS-CoV-2 and characterize them in vitro and in vivo.
Guardado en:
Autores principales: | Alberto A. Amarilla, Julian D. J. Sng, Rhys Parry, Joshua M. Deerain, James R. Potter, Yin Xiang Setoh, Daniel J. Rawle, Thuy T. Le, Naphak Modhiran, Xiaohui Wang, Nias Y. G. Peng, Francisco J. Torres, Alyssa Pyke, Jessica J. Harrison, Morgan E. Freney, Benjamin Liang, Christopher L. D. McMillan, Stacey T. M. Cheung, Darwin J. Da Costa Guevara, Joshua M. Hardy, Mark Bettington, David A. Muller, Fasséli Coulibaly, Frederick Moore, Roy A. Hall, Paul R. Young, Jason M. Mackenzie, Jody Hobson-Peters, Andreas Suhrbier, Daniel Watterson, Alexander A. Khromykh |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2d42390e6b6242feac70593cf3d675b1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses
por: Joshua M. Hardy, et al.
Publicado: (2021) -
Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
por: Andrii Slonchak, et al.
Publicado: (2020) -
<italic toggle="yes">De Novo</italic> Generation and Characterization of New Zika Virus Isolate Using Sequence Data from a Microcephaly Case
por: Yin Xiang Setoh, et al.
Publicado: (2017) -
The architecture and stabilisation of flagellotropic tailed bacteriophages
por: Joshua M. Hardy, et al.
Publicado: (2020) -
A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses
por: Natalie A. Prow, et al.
Publicado: (2018)