Nanometer size silicon particles for hyperpolarized MRI

Abstract Hyperpolarized silicon particles have been shown to exhibit long spin-lattice relaxation times at room temperature, making them interesting as novel MRI probes. Demonstrations of hyperpolarized silicon particle imaging have focused on large micron size particles (average particle size (APS)...

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Autores principales:	Grzegorz Kwiatkowski, Fabian Jähnig, Jonas Steinhauser, Patrick Wespi, Matthias Ernst, Sebastian Kozerke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2d48c3118cfa4af8bc9fe9b9daedd22c
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spelling	oai:doaj.org-article:2d48c3118cfa4af8bc9fe9b9daedd22c2021-12-02T11:52:38ZNanometer size silicon particles for hyperpolarized MRI10.1038/s41598-017-08709-02045-2322https://doaj.org/article/2d48c3118cfa4af8bc9fe9b9daedd22c2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08709-0https://doaj.org/toc/2045-2322Abstract Hyperpolarized silicon particles have been shown to exhibit long spin-lattice relaxation times at room temperature, making them interesting as novel MRI probes. Demonstrations of hyperpolarized silicon particle imaging have focused on large micron size particles (average particle size (APS) = 2.2 μm) as they have, to date, demonstrated much larger polarizations than nanoparticles. We show that also much smaller silicon-29 particles (APS = 55 ± 12 nm) can be hyperpolarized with superior properties. A maximum polarization of 12.6% in the solid state is reported with a spin-lattice relaxation time of 42 min at room temperature thereby opening a new window for MRI applications.Grzegorz KwiatkowskiFabian JähnigJonas SteinhauserPatrick WespiMatthias ErnstSebastian KozerkeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Grzegorz Kwiatkowski Fabian Jähnig Jonas Steinhauser Patrick Wespi Matthias Ernst Sebastian Kozerke Nanometer size silicon particles for hyperpolarized MRI
description	Abstract Hyperpolarized silicon particles have been shown to exhibit long spin-lattice relaxation times at room temperature, making them interesting as novel MRI probes. Demonstrations of hyperpolarized silicon particle imaging have focused on large micron size particles (average particle size (APS) = 2.2 μm) as they have, to date, demonstrated much larger polarizations than nanoparticles. We show that also much smaller silicon-29 particles (APS = 55 ± 12 nm) can be hyperpolarized with superior properties. A maximum polarization of 12.6% in the solid state is reported with a spin-lattice relaxation time of 42 min at room temperature thereby opening a new window for MRI applications.
format	article
author	Grzegorz Kwiatkowski Fabian Jähnig Jonas Steinhauser Patrick Wespi Matthias Ernst Sebastian Kozerke
author_facet	Grzegorz Kwiatkowski Fabian Jähnig Jonas Steinhauser Patrick Wespi Matthias Ernst Sebastian Kozerke
author_sort	Grzegorz Kwiatkowski
title	Nanometer size silicon particles for hyperpolarized MRI
title_short	Nanometer size silicon particles for hyperpolarized MRI
title_full	Nanometer size silicon particles for hyperpolarized MRI
title_fullStr	Nanometer size silicon particles for hyperpolarized MRI
title_full_unstemmed	Nanometer size silicon particles for hyperpolarized MRI
title_sort	nanometer size silicon particles for hyperpolarized mri
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2d48c3118cfa4af8bc9fe9b9daedd22c
work_keys_str_mv	AT grzegorzkwiatkowski nanometersizesiliconparticlesforhyperpolarizedmri AT fabianjahnig nanometersizesiliconparticlesforhyperpolarizedmri AT jonassteinhauser nanometersizesiliconparticlesforhyperpolarizedmri AT patrickwespi nanometersizesiliconparticlesforhyperpolarizedmri AT matthiasernst nanometersizesiliconparticlesforhyperpolarizedmri AT sebastiankozerke nanometersizesiliconparticlesforhyperpolarizedmri
_version_	1718394973115645952

Nanometer size silicon particles for hyperpolarized MRI

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