Solar ultraviolet irradiation induces decorin degradation in human skin likely via neutrophil elastase.

Exposure of human skin to solar ultraviolet (UV) irradiation induces matrix metalloproteinase-1 (MMP-1) activity, which degrades type I collagen fibrils. Type I collagen is the most abundant protein in skin and constitutes the majority of skin connective tissue (dermis). Degradation of collagen fibr...

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Bibliographic Details
Main Authors: Yong Li, Wei Xia, Ying Liu, Henriette A Remmer, John Voorhees, Gary J Fisher
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/2d4a0a7140ed43578339c9a15afb6de8
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