The association of depression and anxiety with pain: a study from NESDA.

Chronic pain is commonly co-morbid with a depressive or anxiety disorder. Objective of this study is to examine the influence of depression, along with anxiety, on pain-related disability, pain intensity, and pain location in a large sample of adults with and without a depressive and/or anxiety diso...

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Autores principales:	Eric W de Heer, Marloes M J G Gerrits, Aartjan T F Beekman, Jack Dekker, Harm W J van Marwijk, Margot W M de Waal, Philip Spinhoven, Brenda W J H Penninx, Christina M van der Feltz-Cornelis
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2d5d13ac5b5e4400b66acfe9b1da43e9
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spelling	oai:doaj.org-article:2d5d13ac5b5e4400b66acfe9b1da43e92021-11-25T05:56:34ZThe association of depression and anxiety with pain: a study from NESDA.1932-620310.1371/journal.pone.0106907https://doaj.org/article/2d5d13ac5b5e4400b66acfe9b1da43e92014-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0106907https://doaj.org/toc/1932-6203Chronic pain is commonly co-morbid with a depressive or anxiety disorder. Objective of this study is to examine the influence of depression, along with anxiety, on pain-related disability, pain intensity, and pain location in a large sample of adults with and without a depressive and/or anxiety disorder. The study population consisted of 2981 participants with a depressive, anxiety, co-morbid depressive and anxiety disorder, remitted disorder or no current disorder (controls). Severity of depressive and anxiety symptoms was also assessed. In separate multinomial regression analyses, the association of presence of depressive or anxiety disorders and symptom severity with the Chronic Pain Grade and location of pain was explored. Presence of a depressive (OR = 6.67; P<.001), anxiety (OR = 4.84; P<.001), or co-morbid depressive and anxiety disorder (OR = 30.26; P<.001) was associated with the Chronic Pain Grade. Moreover, symptom severity was associated with more disabling and severely limiting pain. Also, a remitted depressive or anxiety disorder showed more disabling and severely limiting pain (OR = 3.53; P<.001) as compared to controls. A current anxiety disorder (OR = 2.96; p<.001) and a co-morbid depressive and anxiety disorder (OR = 5.15; P<.001) were more strongly associated with cardio-respiratory pain, than gastro-intestinal or musculoskeletal pain. These findings remain after adjustment for chronic cardio respiratory illness. Patients with a current and remitted depressive and/or anxiety disorder and those with more severe symptoms have more disabling pain and pain of cardio-respiratory nature, than persons without a depressive or anxiety disorder. This warrants further research.Eric W de HeerMarloes M J G GerritsAartjan T F BeekmanJack DekkerHarm W J van MarwijkMargot W M de WaalPhilip SpinhovenBrenda W J H PenninxChristina M van der Feltz-CornelisPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 10, p e106907 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Eric W de Heer Marloes M J G Gerrits Aartjan T F Beekman Jack Dekker Harm W J van Marwijk Margot W M de Waal Philip Spinhoven Brenda W J H Penninx Christina M van der Feltz-Cornelis The association of depression and anxiety with pain: a study from NESDA.
description	Chronic pain is commonly co-morbid with a depressive or anxiety disorder. Objective of this study is to examine the influence of depression, along with anxiety, on pain-related disability, pain intensity, and pain location in a large sample of adults with and without a depressive and/or anxiety disorder. The study population consisted of 2981 participants with a depressive, anxiety, co-morbid depressive and anxiety disorder, remitted disorder or no current disorder (controls). Severity of depressive and anxiety symptoms was also assessed. In separate multinomial regression analyses, the association of presence of depressive or anxiety disorders and symptom severity with the Chronic Pain Grade and location of pain was explored. Presence of a depressive (OR = 6.67; P<.001), anxiety (OR = 4.84; P<.001), or co-morbid depressive and anxiety disorder (OR = 30.26; P<.001) was associated with the Chronic Pain Grade. Moreover, symptom severity was associated with more disabling and severely limiting pain. Also, a remitted depressive or anxiety disorder showed more disabling and severely limiting pain (OR = 3.53; P<.001) as compared to controls. A current anxiety disorder (OR = 2.96; p<.001) and a co-morbid depressive and anxiety disorder (OR = 5.15; P<.001) were more strongly associated with cardio-respiratory pain, than gastro-intestinal or musculoskeletal pain. These findings remain after adjustment for chronic cardio respiratory illness. Patients with a current and remitted depressive and/or anxiety disorder and those with more severe symptoms have more disabling pain and pain of cardio-respiratory nature, than persons without a depressive or anxiety disorder. This warrants further research.
format	article
author	Eric W de Heer Marloes M J G Gerrits Aartjan T F Beekman Jack Dekker Harm W J van Marwijk Margot W M de Waal Philip Spinhoven Brenda W J H Penninx Christina M van der Feltz-Cornelis
author_facet	Eric W de Heer Marloes M J G Gerrits Aartjan T F Beekman Jack Dekker Harm W J van Marwijk Margot W M de Waal Philip Spinhoven Brenda W J H Penninx Christina M van der Feltz-Cornelis
author_sort	Eric W de Heer
title	The association of depression and anxiety with pain: a study from NESDA.
title_short	The association of depression and anxiety with pain: a study from NESDA.
title_full	The association of depression and anxiety with pain: a study from NESDA.
title_fullStr	The association of depression and anxiety with pain: a study from NESDA.
title_full_unstemmed	The association of depression and anxiety with pain: a study from NESDA.
title_sort	association of depression and anxiety with pain: a study from nesda.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/2d5d13ac5b5e4400b66acfe9b1da43e9
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The association of depression and anxiety with pain: a study from NESDA.

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