Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions

Abstract Apis mellifera is an important provider of ecosystem services, and during flight and foraging behaviour is exposed to environmental pollutants including airborne particulate matter (PM). While exposure to insecticides, antibiotics, and herbicides may compromise bee health through alteration...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	G. Papa, G. Di Prisco, G. Spini, E. Puglisi, I. Negri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2d6549d4853248a5abb8d08c5c3ea583
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2d6549d4853248a5abb8d08c5c3ea583
record_format	dspace
spelling	oai:doaj.org-article:2d6549d4853248a5abb8d08c5c3ea5832021-12-02T17:05:12ZAcute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions10.1038/s41598-021-85153-12045-2322https://doaj.org/article/2d6549d4853248a5abb8d08c5c3ea5832021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85153-1https://doaj.org/toc/2045-2322Abstract Apis mellifera is an important provider of ecosystem services, and during flight and foraging behaviour is exposed to environmental pollutants including airborne particulate matter (PM). While exposure to insecticides, antibiotics, and herbicides may compromise bee health through alterations of the gut microbial community, no data are available on the impacts of PM on the bee microbiota. Here we tested the effects of ultrapure Titanium dioxide (TiO2) submicrometric PM (i.e., PM1, less than 1 µm in diameter) on the gut microbiota of adult bees. TiO2 PM1 is widely used as a filler and whitening agent in a range of manufactured objects, and ultrapure TiO2 PM1 is also a common food additive, even if it has been classified by the International Agency for Research on Cancer (IARC) as a possible human carcinogen in Group 2B. Due to its ubiquitous use, honey bees may be severely exposed to TiO2 ingestion through contaminated honey and pollen. Here, we demonstrated that acute and chronic oral administration of ultrapure TiO2 PM1 to adult bees alters the bee microbial community; therefore, airborne PM may represent a further risk factor for the honey bee health, promoting sublethal effects against the gut microbiota.G. PapaG. Di PriscoG. SpiniE. PuglisiI. NegriNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q G. Papa G. Di Prisco G. Spini E. Puglisi I. Negri Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions
description	Abstract Apis mellifera is an important provider of ecosystem services, and during flight and foraging behaviour is exposed to environmental pollutants including airborne particulate matter (PM). While exposure to insecticides, antibiotics, and herbicides may compromise bee health through alterations of the gut microbial community, no data are available on the impacts of PM on the bee microbiota. Here we tested the effects of ultrapure Titanium dioxide (TiO2) submicrometric PM (i.e., PM1, less than 1 µm in diameter) on the gut microbiota of adult bees. TiO2 PM1 is widely used as a filler and whitening agent in a range of manufactured objects, and ultrapure TiO2 PM1 is also a common food additive, even if it has been classified by the International Agency for Research on Cancer (IARC) as a possible human carcinogen in Group 2B. Due to its ubiquitous use, honey bees may be severely exposed to TiO2 ingestion through contaminated honey and pollen. Here, we demonstrated that acute and chronic oral administration of ultrapure TiO2 PM1 to adult bees alters the bee microbial community; therefore, airborne PM may represent a further risk factor for the honey bee health, promoting sublethal effects against the gut microbiota.
format	article
author	G. Papa G. Di Prisco G. Spini E. Puglisi I. Negri
author_facet	G. Papa G. Di Prisco G. Spini E. Puglisi I. Negri
author_sort	G. Papa
title	Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions
title_short	Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions
title_full	Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions
title_fullStr	Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions
title_full_unstemmed	Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions
title_sort	acute and chronic effects of titanium dioxide (tio2) pm1 on honey bee gut microbiota under laboratory conditions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2d6549d4853248a5abb8d08c5c3ea583
work_keys_str_mv	AT gpapa acuteandchroniceffectsoftitaniumdioxidetio2pm1onhoneybeegutmicrobiotaunderlaboratoryconditions AT gdiprisco acuteandchroniceffectsoftitaniumdioxidetio2pm1onhoneybeegutmicrobiotaunderlaboratoryconditions AT gspini acuteandchroniceffectsoftitaniumdioxidetio2pm1onhoneybeegutmicrobiotaunderlaboratoryconditions AT epuglisi acuteandchroniceffectsoftitaniumdioxidetio2pm1onhoneybeegutmicrobiotaunderlaboratoryconditions AT inegri acuteandchroniceffectsoftitaniumdioxidetio2pm1onhoneybeegutmicrobiotaunderlaboratoryconditions
_version_	1718381782012788736

Acute and chronic effects of Titanium dioxide (TiO2) PM1 on honey bee gut microbiota under laboratory conditions

Ejemplares similares