Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
Interneuron subtypes have distinct properties and spatial distributions. Here, the authors show that the molecular-genetic basis of cortical resting-state brain function is shaped by distributions of interneuron-related transcripts and may capture individual differences in schizophrenia risk.
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Nature Portfolio
2020
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oai:doaj.org-article:2d6808f4bbe8432196787073c148df3e2021-12-02T15:02:50ZTranscriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk10.1038/s41467-020-16710-x2041-1723https://doaj.org/article/2d6808f4bbe8432196787073c148df3e2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16710-xhttps://doaj.org/toc/2041-1723Interneuron subtypes have distinct properties and spatial distributions. Here, the authors show that the molecular-genetic basis of cortical resting-state brain function is shaped by distributions of interneuron-related transcripts and may capture individual differences in schizophrenia risk.Kevin M. AndersonMeghan A. CollinsRowena ChinTian GeMonica D. RosenbergAvram J. HolmesNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Kevin M. Anderson Meghan A. Collins Rowena Chin Tian Ge Monica D. Rosenberg Avram J. Holmes Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk |
description |
Interneuron subtypes have distinct properties and spatial distributions. Here, the authors show that the molecular-genetic basis of cortical resting-state brain function is shaped by distributions of interneuron-related transcripts and may capture individual differences in schizophrenia risk. |
format |
article |
author |
Kevin M. Anderson Meghan A. Collins Rowena Chin Tian Ge Monica D. Rosenberg Avram J. Holmes |
author_facet |
Kevin M. Anderson Meghan A. Collins Rowena Chin Tian Ge Monica D. Rosenberg Avram J. Holmes |
author_sort |
Kevin M. Anderson |
title |
Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk |
title_short |
Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk |
title_full |
Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk |
title_fullStr |
Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk |
title_full_unstemmed |
Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk |
title_sort |
transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/2d6808f4bbe8432196787073c148df3e |
work_keys_str_mv |
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1718389068088213504 |