Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk

Interneuron subtypes have distinct properties and spatial distributions. Here, the authors show that the molecular-genetic basis of cortical resting-state brain function is shaped by distributions of interneuron-related transcripts and may capture individual differences in schizophrenia risk.

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Autores principales: Kevin M. Anderson, Meghan A. Collins, Rowena Chin, Tian Ge, Monica D. Rosenberg, Avram J. Holmes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2d6808f4bbe8432196787073c148df3e
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spelling oai:doaj.org-article:2d6808f4bbe8432196787073c148df3e2021-12-02T15:02:50ZTranscriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk10.1038/s41467-020-16710-x2041-1723https://doaj.org/article/2d6808f4bbe8432196787073c148df3e2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16710-xhttps://doaj.org/toc/2041-1723Interneuron subtypes have distinct properties and spatial distributions. Here, the authors show that the molecular-genetic basis of cortical resting-state brain function is shaped by distributions of interneuron-related transcripts and may capture individual differences in schizophrenia risk.Kevin M. AndersonMeghan A. CollinsRowena ChinTian GeMonica D. RosenbergAvram J. HolmesNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kevin M. Anderson
Meghan A. Collins
Rowena Chin
Tian Ge
Monica D. Rosenberg
Avram J. Holmes
Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
description Interneuron subtypes have distinct properties and spatial distributions. Here, the authors show that the molecular-genetic basis of cortical resting-state brain function is shaped by distributions of interneuron-related transcripts and may capture individual differences in schizophrenia risk.
format article
author Kevin M. Anderson
Meghan A. Collins
Rowena Chin
Tian Ge
Monica D. Rosenberg
Avram J. Holmes
author_facet Kevin M. Anderson
Meghan A. Collins
Rowena Chin
Tian Ge
Monica D. Rosenberg
Avram J. Holmes
author_sort Kevin M. Anderson
title Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
title_short Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
title_full Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
title_fullStr Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
title_full_unstemmed Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
title_sort transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/2d6808f4bbe8432196787073c148df3e
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