Diabetic muscle infarction: often misdiagnosed and mismanaged

Mohamud A Verjee,1 Nael Amin Abdelsamad,2 Salman Qureshi,3,4 Rayaz A Malik1,5 1Department of Medicine, Weill Cornell Medicine – Qatar, Qatar Foundation, Education City, Doha, Qatar; 2Department of Paediatrics, University of Utah, Salt Lake City, UT 84112, USA; 3Department of Radiology, Uni...

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Autores principales:	Verjee MA, Abdelsamad NA, Qureshi S, Malik RA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Muscle infarction neuropathy microvascular edema striations. Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/2d69455a83f24ec9ac05463889450b30
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spelling	oai:doaj.org-article:2d69455a83f24ec9ac05463889450b302021-12-02T09:04:59ZDiabetic muscle infarction: often misdiagnosed and mismanaged1178-7007https://doaj.org/article/2d69455a83f24ec9ac05463889450b302019-03-01T00:00:00Zhttps://www.dovepress.com/diabetic-muscle-infarction-often-misdiagnosed-and-mismanaged-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Mohamud A Verjee,1 Nael Amin Abdelsamad,2 Salman Qureshi,3,4 Rayaz A Malik1,5 1Department of Medicine, Weill Cornell Medicine – Qatar, Qatar Foundation, Education City, Doha, Qatar; 2Department of Paediatrics, University of Utah, Salt Lake City, UT 84112, USA; 3Department of Radiology, University of Manchester, Manchester M13 9PL, UK; 4Department of Radiology, Hamad Medical Corporation, Doha, Qatar; 5Institute of Cardiovascular Medicine, University of Manchester, Manchester, M13 9PL, UK Abstract: A patient with type 2 diabetes, retinopathy, neuropathy, and nephropathy presented with severe right distal thigh pain, which awoke him from sleep. He was diagnosed with musculoskeletal pain and discharged home. Two days later, the severity of pain increased in his right thigh and, subsequently, he developed pain in the proximal lateral aspect of his left thigh, for which he returned to hospital. He had elevated creatine kinase and myoglobin levels. An ultrasound of the right thigh identified a loss of definition of the normal muscular striations and subcutaneous edema. On MRI, the axial STIR image demonstrated extensive T2 hyperintensity in the right vastus medialis and left vastus lateralis, consistent with the diagnosis of diabetic muscle infarction (DMI). This presentation emphasizes the need for a thorough patient history and physical examination, and the importance of directed imaging for the prompt diagnosis of DMI. Keywords: muscle infarction, edema, microvascular, nephropathy, neuropathy, retinopathy, striationsVerjee MAAbdelsamad NAQureshi SMalik RADove Medical PressarticleMuscle infarctionneuropathymicrovascularedemastriations.Specialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 12, Pp 285-290 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Muscle infarction neuropathy microvascular edema striations. Specialties of internal medicine RC581-951
spellingShingle	Muscle infarction neuropathy microvascular edema striations. Specialties of internal medicine RC581-951 Verjee MA Abdelsamad NA Qureshi S Malik RA Diabetic muscle infarction: often misdiagnosed and mismanaged
description	Mohamud A Verjee,1 Nael Amin Abdelsamad,2 Salman Qureshi,3,4 Rayaz A Malik1,5 1Department of Medicine, Weill Cornell Medicine – Qatar, Qatar Foundation, Education City, Doha, Qatar; 2Department of Paediatrics, University of Utah, Salt Lake City, UT 84112, USA; 3Department of Radiology, University of Manchester, Manchester M13 9PL, UK; 4Department of Radiology, Hamad Medical Corporation, Doha, Qatar; 5Institute of Cardiovascular Medicine, University of Manchester, Manchester, M13 9PL, UK Abstract: A patient with type 2 diabetes, retinopathy, neuropathy, and nephropathy presented with severe right distal thigh pain, which awoke him from sleep. He was diagnosed with musculoskeletal pain and discharged home. Two days later, the severity of pain increased in his right thigh and, subsequently, he developed pain in the proximal lateral aspect of his left thigh, for which he returned to hospital. He had elevated creatine kinase and myoglobin levels. An ultrasound of the right thigh identified a loss of definition of the normal muscular striations and subcutaneous edema. On MRI, the axial STIR image demonstrated extensive T2 hyperintensity in the right vastus medialis and left vastus lateralis, consistent with the diagnosis of diabetic muscle infarction (DMI). This presentation emphasizes the need for a thorough patient history and physical examination, and the importance of directed imaging for the prompt diagnosis of DMI. Keywords: muscle infarction, edema, microvascular, nephropathy, neuropathy, retinopathy, striations
format	article
author	Verjee MA Abdelsamad NA Qureshi S Malik RA
author_facet	Verjee MA Abdelsamad NA Qureshi S Malik RA
author_sort	Verjee MA
title	Diabetic muscle infarction: often misdiagnosed and mismanaged
title_short	Diabetic muscle infarction: often misdiagnosed and mismanaged
title_full	Diabetic muscle infarction: often misdiagnosed and mismanaged
title_fullStr	Diabetic muscle infarction: often misdiagnosed and mismanaged
title_full_unstemmed	Diabetic muscle infarction: often misdiagnosed and mismanaged
title_sort	diabetic muscle infarction: often misdiagnosed and mismanaged
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/2d69455a83f24ec9ac05463889450b30
work_keys_str_mv	AT verjeema diabeticmuscleinfarctionoftenmisdiagnosedandmismanaged AT abdelsamadna diabeticmuscleinfarctionoftenmisdiagnosedandmismanaged AT qureshis diabeticmuscleinfarctionoftenmisdiagnosedandmismanaged AT malikra diabeticmuscleinfarctionoftenmisdiagnosedandmismanaged
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Diabetic muscle infarction: often misdiagnosed and mismanaged

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