Misalignment with the external light environment drives metabolic and cardiac dysfunction

The misalignment between internal circadian rhythm and the day-night cycle can be caused by genetic, behavioural and environmental factors, and may have a profound impact on human physiology. Here West et al. show that desynchrony between the internal clock and the external environment alter metabol...

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Autores principales: Alexander C. West, Laura Smith, David W. Ray, Andrew S. I. Loudon, Timothy M. Brown, David A. Bechtold
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2d72018ac5b048df938b60e64d498dc6
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Sumario:The misalignment between internal circadian rhythm and the day-night cycle can be caused by genetic, behavioural and environmental factors, and may have a profound impact on human physiology. Here West et al. show that desynchrony between the internal clock and the external environment alter metabolic parameters and cardiac function in mice.