Misalignment with the external light environment drives metabolic and cardiac dysfunction

The misalignment between internal circadian rhythm and the day-night cycle can be caused by genetic, behavioural and environmental factors, and may have a profound impact on human physiology. Here West et al. show that desynchrony between the internal clock and the external environment alter metabol...

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Autores principales:	Alexander C. West, Laura Smith, David W. Ray, Andrew S. I. Loudon, Timothy M. Brown, David A. Bechtold
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2d72018ac5b048df938b60e64d498dc6
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spelling	oai:doaj.org-article:2d72018ac5b048df938b60e64d498dc62021-12-02T17:06:17ZMisalignment with the external light environment drives metabolic and cardiac dysfunction10.1038/s41467-017-00462-22041-1723https://doaj.org/article/2d72018ac5b048df938b60e64d498dc62017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00462-2https://doaj.org/toc/2041-1723The misalignment between internal circadian rhythm and the day-night cycle can be caused by genetic, behavioural and environmental factors, and may have a profound impact on human physiology. Here West et al. show that desynchrony between the internal clock and the external environment alter metabolic parameters and cardiac function in mice.Alexander C. WestLaura SmithDavid W. RayAndrew S. I. LoudonTimothy M. BrownDavid A. BechtoldNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexander C. West Laura Smith David W. Ray Andrew S. I. Loudon Timothy M. Brown David A. Bechtold Misalignment with the external light environment drives metabolic and cardiac dysfunction
description	The misalignment between internal circadian rhythm and the day-night cycle can be caused by genetic, behavioural and environmental factors, and may have a profound impact on human physiology. Here West et al. show that desynchrony between the internal clock and the external environment alter metabolic parameters and cardiac function in mice.
format	article
author	Alexander C. West Laura Smith David W. Ray Andrew S. I. Loudon Timothy M. Brown David A. Bechtold
author_facet	Alexander C. West Laura Smith David W. Ray Andrew S. I. Loudon Timothy M. Brown David A. Bechtold
author_sort	Alexander C. West
title	Misalignment with the external light environment drives metabolic and cardiac dysfunction
title_short	Misalignment with the external light environment drives metabolic and cardiac dysfunction
title_full	Misalignment with the external light environment drives metabolic and cardiac dysfunction
title_fullStr	Misalignment with the external light environment drives metabolic and cardiac dysfunction
title_full_unstemmed	Misalignment with the external light environment drives metabolic and cardiac dysfunction
title_sort	misalignment with the external light environment drives metabolic and cardiac dysfunction
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2d72018ac5b048df938b60e64d498dc6
work_keys_str_mv	AT alexandercwest misalignmentwiththeexternallightenvironmentdrivesmetabolicandcardiacdysfunction AT laurasmith misalignmentwiththeexternallightenvironmentdrivesmetabolicandcardiacdysfunction AT davidwray misalignmentwiththeexternallightenvironmentdrivesmetabolicandcardiacdysfunction AT andrewsiloudon misalignmentwiththeexternallightenvironmentdrivesmetabolicandcardiacdysfunction AT timothymbrown misalignmentwiththeexternallightenvironmentdrivesmetabolicandcardiacdysfunction AT davidabechtold misalignmentwiththeexternallightenvironmentdrivesmetabolicandcardiacdysfunction
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Misalignment with the external light environment drives metabolic and cardiac dysfunction

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