Role of backbone strain in de novo design of complex α/β protein structures
The authors show that consideration of global backbone strain enables successful de novo design of larger αβ-proteins with five- and six- stranded β-sheets flanked by α-helices.
Guardado en:
Autores principales: | Nobuyasu Koga, Rie Koga, Gaohua Liu, Javier Castellanos, Gaetano T. Montelione, David Baker |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2d79dbe5ccf94845993306b13efb4de2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The register shift rules for βαβ-motifs for de novo protein design.
por: Hiroto Murata, et al.
Publicado: (2021) -
Critical role of backbone coordination in the mRNA recognition by RNA induced silencing complex
por: Lizhe Zhu, et al.
Publicado: (2021) -
Serial disparity in the carnivoran backbone unveils a complex adaptive role in metameric evolution
por: Borja Figueirido, et al.
Publicado: (2021) -
Author Correction: Extracting backbones in weighted modular complex networks
por: Zakariya Ghalmane, et al.
Publicado: (2021) -
Predictions of Backbone Dynamics in Intrinsically Disordered Proteins Using De Novo Fragment-Based Protein Structure Predictions
por: Tomasz Kosciolek, et al.
Publicado: (2017)