CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation

Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation.

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Autores principales: Gentaro Izumi, Hideki Nakano, Keiko Nakano, Gregory S. Whitehead, Sara A. Grimm, Michael B. Fessler, Peer W. Karmaus, Donald N. Cook
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2d7e7a34ad9741c7b9cd97853b90ab3b
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spelling oai:doaj.org-article:2d7e7a34ad9741c7b9cd97853b90ab3b2021-12-02T18:01:16ZCD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation10.1038/s41467-021-25307-x2041-1723https://doaj.org/article/2d7e7a34ad9741c7b9cd97853b90ab3b2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25307-xhttps://doaj.org/toc/2041-1723Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation.Gentaro IzumiHideki NakanoKeiko NakanoGregory S. WhiteheadSara A. GrimmMichael B. FesslerPeer W. KarmausDonald N. CookNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gentaro Izumi
Hideki Nakano
Keiko Nakano
Gregory S. Whitehead
Sara A. Grimm
Michael B. Fessler
Peer W. Karmaus
Donald N. Cook
CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation
description Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation.
format article
author Gentaro Izumi
Hideki Nakano
Keiko Nakano
Gregory S. Whitehead
Sara A. Grimm
Michael B. Fessler
Peer W. Karmaus
Donald N. Cook
author_facet Gentaro Izumi
Hideki Nakano
Keiko Nakano
Gregory S. Whitehead
Sara A. Grimm
Michael B. Fessler
Peer W. Karmaus
Donald N. Cook
author_sort Gentaro Izumi
title CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation
title_short CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation
title_full CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation
title_fullStr CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation
title_full_unstemmed CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation
title_sort cd11b+ lung dendritic cells at different stages of maturation induce th17 or th2 differentiation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/2d7e7a34ad9741c7b9cd97853b90ab3b
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