CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation
Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation.
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Nature Portfolio
2021
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oai:doaj.org-article:2d7e7a34ad9741c7b9cd97853b90ab3b2021-12-02T18:01:16ZCD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation10.1038/s41467-021-25307-x2041-1723https://doaj.org/article/2d7e7a34ad9741c7b9cd97853b90ab3b2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25307-xhttps://doaj.org/toc/2041-1723Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation.Gentaro IzumiHideki NakanoKeiko NakanoGregory S. WhiteheadSara A. GrimmMichael B. FesslerPeer W. KarmausDonald N. CookNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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Science Q Gentaro Izumi Hideki Nakano Keiko Nakano Gregory S. Whitehead Sara A. Grimm Michael B. Fessler Peer W. Karmaus Donald N. Cook CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation |
description |
Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation. |
format |
article |
author |
Gentaro Izumi Hideki Nakano Keiko Nakano Gregory S. Whitehead Sara A. Grimm Michael B. Fessler Peer W. Karmaus Donald N. Cook |
author_facet |
Gentaro Izumi Hideki Nakano Keiko Nakano Gregory S. Whitehead Sara A. Grimm Michael B. Fessler Peer W. Karmaus Donald N. Cook |
author_sort |
Gentaro Izumi |
title |
CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation |
title_short |
CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation |
title_full |
CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation |
title_fullStr |
CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation |
title_full_unstemmed |
CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation |
title_sort |
cd11b+ lung dendritic cells at different stages of maturation induce th17 or th2 differentiation |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/2d7e7a34ad9741c7b9cd97853b90ab3b |
work_keys_str_mv |
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_version_ |
1718378977559576576 |