A critical appraisal of the clinical utility of proton therapy in oncology

Dongxu WangDepartment of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAAbstract: Proton therapy is an emerging technology for providing radiation therapy to cancer patients. The depth dose distribution of a proton beam makes it a preferable radiation modality as it...

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Autor principal:	Wang D
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/2d81280528444f39959c3f6e3083575f
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spelling	oai:doaj.org-article:2d81280528444f39959c3f6e3083575f2021-12-02T01:15:27ZA critical appraisal of the clinical utility of proton therapy in oncology1179-1470https://doaj.org/article/2d81280528444f39959c3f6e3083575f2015-10-01T00:00:00Zhttps://www.dovepress.com/a-critical-appraisal-of-the-clinical-utility-of-proton-therapy-in-onco-peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Dongxu WangDepartment of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAAbstract: Proton therapy is an emerging technology for providing radiation therapy to cancer patients. The depth dose distribution of a proton beam makes it a preferable radiation modality as it reduces radiation to the healthy tissue outside the tumor, compared with conventional photon therapy. While theoretically beneficial, its clinical values are still being demonstrated from the increasing number of patients treated with proton therapy, from several dozen proton therapy centers around the world. High equipment and facility costs are often the major obstacle for its wider adoption. Because of the high cost and lack of definite clinical evidence of its superiority, proton therapy treatment faces criticism on its cost-effectiveness. Technological development is causing a gradual lowering of costs, and research and clinical studies are providing further evidence on its clinical utility.Keywords: proton therapy, radiation, cancer, oncologyWang DDove Medical PressarticleMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2015, Iss default, Pp 439-446 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5
spellingShingle	Medical technology R855-855.5 Wang D A critical appraisal of the clinical utility of proton therapy in oncology
description	Dongxu WangDepartment of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAAbstract: Proton therapy is an emerging technology for providing radiation therapy to cancer patients. The depth dose distribution of a proton beam makes it a preferable radiation modality as it reduces radiation to the healthy tissue outside the tumor, compared with conventional photon therapy. While theoretically beneficial, its clinical values are still being demonstrated from the increasing number of patients treated with proton therapy, from several dozen proton therapy centers around the world. High equipment and facility costs are often the major obstacle for its wider adoption. Because of the high cost and lack of definite clinical evidence of its superiority, proton therapy treatment faces criticism on its cost-effectiveness. Technological development is causing a gradual lowering of costs, and research and clinical studies are providing further evidence on its clinical utility.Keywords: proton therapy, radiation, cancer, oncology
format	article
author	Wang D
author_facet	Wang D
author_sort	Wang D
title	A critical appraisal of the clinical utility of proton therapy in oncology
title_short	A critical appraisal of the clinical utility of proton therapy in oncology
title_full	A critical appraisal of the clinical utility of proton therapy in oncology
title_fullStr	A critical appraisal of the clinical utility of proton therapy in oncology
title_full_unstemmed	A critical appraisal of the clinical utility of proton therapy in oncology
title_sort	critical appraisal of the clinical utility of proton therapy in oncology
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/2d81280528444f39959c3f6e3083575f
work_keys_str_mv	AT wangd acriticalappraisaloftheclinicalutilityofprotontherapyinoncology AT wangd criticalappraisaloftheclinicalutilityofprotontherapyinoncology
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A critical appraisal of the clinical utility of proton therapy in oncology

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