Mutational profile of GNAQQ209 in human tumors.
<h4>Background</h4>Frequent somatic mutations have recently been identified in the ras-like domain of the heterotrimeric G protein alpha-subunit (GNAQ) in blue naevi 83%, malignant blue naevi (50%) and ocular melanoma of the uvea (46%). The mutations exclusively affect codon 209 and resu...
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Autores principales: | Simona Lamba, Lara Felicioni, Fiamma Buttitta, Fonnet E Bleeker, Sara Malatesta, Vincenzo Corbo, Aldo Scarpa, Monica Rodolfo, Margaret Knowles, Milo Frattini, Antonio Marchetti, Alberto Bardelli |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/2d88680c0dff4111a21046556cc7fe9c |
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