L-carnitine ameliorates the muscle wasting of cancer cachexia through the AKT/FOXO3a/MaFbx axis

Abstract Background Recent studies suggest potential benefits of applying L-carnitine in the treatment of cancer cachexia, but the precise mechanisms underlying these benefits remain unknown. This study was conducted to determine the mechanism by which L-carnitine reduces cancer cachexia. Methods C2...

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Bibliographic Details
Main Authors: Changpeng Wu, Mingxing Zhu, Zongliang Lu, Yaowen Zhang, Long Li, Na Li, Liangyu Yin, He Wang, Wei Song, Hongxia Xu
Format: article
Language:EN
Published: BMC 2021
Subjects:
AKT
Online Access:https://doaj.org/article/2d96e81ea85d4a71b0776218586d425c
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