Alternative Evolutionary Pathways for Drug-Resistant Small Colony Variant Mutants in <italic toggle="yes">Staphylococcus aureus</italic>

ABSTRACT Staphylococcus aureus is known to generate small colony variants (SCVs) that are resistant to aminoglycoside antibiotics and can cause persistent and recurrent infections. The SCV phenotype is unstable, and compensatory mutations lead to restored growth, usually with loss of resistance. How...

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Bibliographic Details
Main Authors: Sha Cao, Douglas L. Huseby, Gerrit Brandis, Diarmaid Hughes
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
ATP
Online Access:https://doaj.org/article/2d9f917113e745adac96b3ae636a6375
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