Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria

Garcia-Senosiain et al developed an in vitro opsonic phagocytosis (OP) assay using peripheral blood leukocytes that enabled quantification of the contribution of each phagocytic cell type in the OP of Plasmodium falciparum blood-stage merozoites, which have been associated with malaria protection. U...

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Autores principales:	Asier Garcia-Senosiain, Ikhlaq Hussain Kana, Subhash Singh, Manoj Kumar Das, Morten Hanefeld Dziegiel, Sanne Hertegonne, Bright Adu, Michael Theisen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/2da18a4ab8754c3db06f3fa3163abde9
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spelling	oai:doaj.org-article:2da18a4ab8754c3db06f3fa3163abde92021-12-02T18:51:45ZNeutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria10.1038/s42003-021-02511-52399-3642https://doaj.org/article/2da18a4ab8754c3db06f3fa3163abde92021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02511-5https://doaj.org/toc/2399-3642Garcia-Senosiain et al developed an in vitro opsonic phagocytosis (OP) assay using peripheral blood leukocytes that enabled quantification of the contribution of each phagocytic cell type in the OP of Plasmodium falciparum blood-stage merozoites, which have been associated with malaria protection. Using patient samples from Ghana and India, they demonstrate that peripheral blood neutrophils are the main phagocytes of P. falciparum blood-stage merozoitesAsier Garcia-SenosiainIkhlaq Hussain KanaSubhash SinghManoj Kumar DasMorten Hanefeld DziegielSanne HertegonneBright AduMichael TheisenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Asier Garcia-Senosiain Ikhlaq Hussain Kana Subhash Singh Manoj Kumar Das Morten Hanefeld Dziegiel Sanne Hertegonne Bright Adu Michael Theisen Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
description	Garcia-Senosiain et al developed an in vitro opsonic phagocytosis (OP) assay using peripheral blood leukocytes that enabled quantification of the contribution of each phagocytic cell type in the OP of Plasmodium falciparum blood-stage merozoites, which have been associated with malaria protection. Using patient samples from Ghana and India, they demonstrate that peripheral blood neutrophils are the main phagocytes of P. falciparum blood-stage merozoites
format	article
author	Asier Garcia-Senosiain Ikhlaq Hussain Kana Subhash Singh Manoj Kumar Das Morten Hanefeld Dziegiel Sanne Hertegonne Bright Adu Michael Theisen
author_facet	Asier Garcia-Senosiain Ikhlaq Hussain Kana Subhash Singh Manoj Kumar Das Morten Hanefeld Dziegiel Sanne Hertegonne Bright Adu Michael Theisen
author_sort	Asier Garcia-Senosiain
title	Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
title_short	Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
title_full	Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
title_fullStr	Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
title_full_unstemmed	Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
title_sort	neutrophils dominate in opsonic phagocytosis of p. falciparum blood-stage merozoites and protect against febrile malaria
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2da18a4ab8754c3db06f3fa3163abde9
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Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria

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