Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape

Jonathan Sulc et al. use principal component analysis and Mendelian randomization to conduct a comprehensive analysis of 14 body morphology metrics using data from the UK Biobank. Their results suggest that body size and adiposity have distinct impacts on obesity-related outcomes and highlight a BMI...

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Autores principales: Jonathan Sulc, Anthony Sonrel, Ninon Mounier, Chiara Auwerx, Eirini Marouli, Liza Darrous, Bogdan Draganski, Tuomas O. Kilpeläinen, Peter Joshi, Ruth J. F. Loos, Zoltán Kutalik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2da3bcef86474fd78e31f2affd509a21
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