Contrasted TCRβ diversity of CD8+ and CD8- T cells in rainbow trout.
Teleost fish express highly diverse naive TCRβ (TRB) repertoires and mount strong public and private clonal responses upon infection with pathogens. Fish T cells express typical markers such as CD8, CD4-1 and CD4-2, CD3, CD28 and CTLA4. Fish CD8(+) T cells have been shown to be responsible for antig...
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Auteurs principaux: | Rosario Castro, Fumio Takizawa, Wahiba Chaara, Aurélie Lunazzi, Thi Huong Dang, Bernd Koellner, Edwige Quillet, Adrien Six, Uwe Fischer, Pierre Boudinot |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Sujets: | |
Accès en ligne: | https://doaj.org/article/2da93e94442d4a80a7921a7214145dcd |
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