Contrasted TCRβ diversity of CD8+ and CD8- T cells in rainbow trout.

Teleost fish express highly diverse naive TCRβ (TRB) repertoires and mount strong public and private clonal responses upon infection with pathogens. Fish T cells express typical markers such as CD8, CD4-1 and CD4-2, CD3, CD28 and CTLA4. Fish CD8(+) T cells have been shown to be responsible for antig...

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Autores principales: Rosario Castro, Fumio Takizawa, Wahiba Chaara, Aurélie Lunazzi, Thi Huong Dang, Bernd Koellner, Edwige Quillet, Adrien Six, Uwe Fischer, Pierre Boudinot
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/2da93e94442d4a80a7921a7214145dcd
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