Current options for the treatment of optic neuritis
John H Pula,1 Christopher J MacDonald21Division of Neuro-ophthalmology, University of Illinois College of Medicine at Peoria, Peoria; 2University of Illinois College of Medicine at Urbana-Champaign, Champaign, IL, USAAbstract: Optic neuritis can be defined as typical (associated with multiple sclero...
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Dove Medical Press
2012
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oai:doaj.org-article:2daae45bcc504f38bf3ad819b008ba0f2021-12-02T09:50:31ZCurrent options for the treatment of optic neuritis1177-54671177-5483https://doaj.org/article/2daae45bcc504f38bf3ad819b008ba0f2012-07-01T00:00:00Zhttp://www.dovepress.com/current-options-for-the-treatment-of-optic-neuritis-a10563https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483John H Pula,1 Christopher J MacDonald21Division of Neuro-ophthalmology, University of Illinois College of Medicine at Peoria, Peoria; 2University of Illinois College of Medicine at Urbana-Champaign, Champaign, IL, USAAbstract: Optic neuritis can be defined as typical (associated with multiple sclerosis, improving independent of steroid treatment), or atypical (not associated with multiple sclerosis, steroid-dependent improvement). Causes of atypical optic neuritis include connective tissue diseases (eg, lupus), vasculitis, sarcoidosis, or neuromyelitis optica. In this manuscript, updated treatment options for both typical and atypical optic neuritis are reviewed. Conventional treatments, such as corticosteroids, therapeutic plasma exchange, and intravenous immunoglobulin therapy are all discussed with commentary regarding evidence-based outcomes. Less commonly used treatments and novel purported therapies for optic neuritis are also reviewed. Special scenarios in the treatment of optic neuritis – pediatric optic neuritis, acute demyelinating encephalomyelitis, and optic neuritis occurring during pregnancy – are specifically examined.Keywords: optic neuritis, optic neuropathy, treatment, neuroophthalmologyPula JHMacDonald CJDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1211-1223 (2012) |
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Ophthalmology RE1-994 Pula JH MacDonald CJ Current options for the treatment of optic neuritis |
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John H Pula,1 Christopher J MacDonald21Division of Neuro-ophthalmology, University of Illinois College of Medicine at Peoria, Peoria; 2University of Illinois College of Medicine at Urbana-Champaign, Champaign, IL, USAAbstract: Optic neuritis can be defined as typical (associated with multiple sclerosis, improving independent of steroid treatment), or atypical (not associated with multiple sclerosis, steroid-dependent improvement). Causes of atypical optic neuritis include connective tissue diseases (eg, lupus), vasculitis, sarcoidosis, or neuromyelitis optica. In this manuscript, updated treatment options for both typical and atypical optic neuritis are reviewed. Conventional treatments, such as corticosteroids, therapeutic plasma exchange, and intravenous immunoglobulin therapy are all discussed with commentary regarding evidence-based outcomes. Less commonly used treatments and novel purported therapies for optic neuritis are also reviewed. Special scenarios in the treatment of optic neuritis – pediatric optic neuritis, acute demyelinating encephalomyelitis, and optic neuritis occurring during pregnancy – are specifically examined.Keywords: optic neuritis, optic neuropathy, treatment, neuroophthalmology |
format |
article |
author |
Pula JH MacDonald CJ |
author_facet |
Pula JH MacDonald CJ |
author_sort |
Pula JH |
title |
Current options for the treatment of optic neuritis |
title_short |
Current options for the treatment of optic neuritis |
title_full |
Current options for the treatment of optic neuritis |
title_fullStr |
Current options for the treatment of optic neuritis |
title_full_unstemmed |
Current options for the treatment of optic neuritis |
title_sort |
current options for the treatment of optic neuritis |
publisher |
Dove Medical Press |
publishDate |
2012 |
url |
https://doaj.org/article/2daae45bcc504f38bf3ad819b008ba0f |
work_keys_str_mv |
AT pulajh currentoptionsforthetreatmentofopticneuritis AT macdonaldcj currentoptionsforthetreatmentofopticneuritis |
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1718397995243798528 |