FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients. Study Design: Prospective, cross-sectional analytical study. Place and Duration of Study: This study c...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Army Medical College Rawalpindi
2019
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/2dabfebb0cc24c4991d4c5f917c87c36 |
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| Sumario: | Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients.
Study Design: Prospective, cross-sectional analytical study.
Place and Duration of Study: This study conducted in the emergency department of Punjab Institute of cardiology, Lahore Pakistan, from Mar 2017 to Jun 2018.
Patients and Methods: Patients with advanced 2nd degree and 3rd degree AV blocks, diagnosed on a 12-lead electrocardiogram (ECG), and no ischemic changes on the ECG were included. hs-TnT levels were done for all patients. All patients filled a preformed questionnaire. Data were entered and analyzed using IBM-SPSS-23.
Results: Of the 138 patients recruited, 60.9% were male patients. The mean age of the study participants was 63.13 ± 14.73 years. Syncope was the most common presentation (78.3%). hs-TnT levels were elevated in 55.8% participants. Elevated Trop T levels were more common in male patients (63.6%). Elevated Trop T levels were significantly associated with co-morbidities including diabetes, hypertension, and smoking, and clinical presence of chest pain and syncope (p>0.05).
Conclusion: Patients with non-ischemic high-grade AV blocks present with syncope. Even in absence of ischemia, troponin levels were seen in many participants. Elevated Trop T levels cannot be considered pathognomonic for myocardial ischemia. |
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