FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES

Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients. Study Design: Prospective, cross-sectional analytical study. Place and Duration of Study: This study c...

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Autores principales: Hafiz Abdul Manaan, Abdul Sattar, Imran Saleem, Shamila Afshan
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Publicado: Army Medical College Rawalpindi 2019
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spelling oai:doaj.org-article:2dabfebb0cc24c4991d4c5f917c87c362021-11-11T05:28:37ZFREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES0030-96482411-8842https://doaj.org/article/2dabfebb0cc24c4991d4c5f917c87c362019-08-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3222/2330https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients. Study Design: Prospective, cross-sectional analytical study. Place and Duration of Study: This study conducted in the emergency department of Punjab Institute of cardiology, Lahore Pakistan, from Mar 2017 to Jun 2018. Patients and Methods: Patients with advanced 2nd degree and 3rd degree AV blocks, diagnosed on a 12-lead electrocardiogram (ECG), and no ischemic changes on the ECG were included. hs-TnT levels were done for all patients. All patients filled a preformed questionnaire. Data were entered and analyzed using IBM-SPSS-23. Results: Of the 138 patients recruited, 60.9% were male patients. The mean age of the study participants was 63.13 ± 14.73 years. Syncope was the most common presentation (78.3%). hs-TnT levels were elevated in 55.8% participants. Elevated Trop T levels were more common in male patients (63.6%). Elevated Trop T levels were significantly associated with co-morbidities including diabetes, hypertension, and smoking, and clinical presence of chest pain and syncope (p>0.05). Conclusion: Patients with non-ischemic high-grade AV blocks present with syncope. Even in absence of ischemia, troponin levels were seen in many participants. Elevated Trop T levels cannot be considered pathognomonic for myocardial ischemia.Hafiz Abdul ManaanAbdul SattarImran SaleemShamila AfshanArmy Medical College Rawalpindiarticleatrioventricular blockhigh-grade heart blockelevated troponin tMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 901-904 (2019)
institution DOAJ
collection DOAJ
language EN
topic atrioventricular block
high-grade heart block
elevated troponin t
Medicine
R
Medicine (General)
R5-920
spellingShingle atrioventricular block
high-grade heart block
elevated troponin t
Medicine
R
Medicine (General)
R5-920
Hafiz Abdul Manaan
Abdul Sattar
Imran Saleem
Shamila Afshan
FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
description Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients. Study Design: Prospective, cross-sectional analytical study. Place and Duration of Study: This study conducted in the emergency department of Punjab Institute of cardiology, Lahore Pakistan, from Mar 2017 to Jun 2018. Patients and Methods: Patients with advanced 2nd degree and 3rd degree AV blocks, diagnosed on a 12-lead electrocardiogram (ECG), and no ischemic changes on the ECG were included. hs-TnT levels were done for all patients. All patients filled a preformed questionnaire. Data were entered and analyzed using IBM-SPSS-23. Results: Of the 138 patients recruited, 60.9% were male patients. The mean age of the study participants was 63.13 ± 14.73 years. Syncope was the most common presentation (78.3%). hs-TnT levels were elevated in 55.8% participants. Elevated Trop T levels were more common in male patients (63.6%). Elevated Trop T levels were significantly associated with co-morbidities including diabetes, hypertension, and smoking, and clinical presence of chest pain and syncope (p>0.05). Conclusion: Patients with non-ischemic high-grade AV blocks present with syncope. Even in absence of ischemia, troponin levels were seen in many participants. Elevated Trop T levels cannot be considered pathognomonic for myocardial ischemia.
format article
author Hafiz Abdul Manaan
Abdul Sattar
Imran Saleem
Shamila Afshan
author_facet Hafiz Abdul Manaan
Abdul Sattar
Imran Saleem
Shamila Afshan
author_sort Hafiz Abdul Manaan
title FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
title_short FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
title_full FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
title_fullStr FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
title_full_unstemmed FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
title_sort frequency of elevated high-sensitivity troponin t and associated cardiac predictors in high-grade atrioventricular block patients with non-ischemic ecg changes
publisher Army Medical College Rawalpindi
publishDate 2019
url https://doaj.org/article/2dabfebb0cc24c4991d4c5f917c87c36
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AT imransaleem frequencyofelevatedhighsensitivitytroponintandassociatedcardiacpredictorsinhighgradeatrioventricularblockpatientswithnonischemicecgchanges
AT shamilaafshan frequencyofelevatedhighsensitivitytroponintandassociatedcardiacpredictorsinhighgradeatrioventricularblockpatientswithnonischemicecgchanges
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