FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES
Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients. Study Design: Prospective, cross-sectional analytical study. Place and Duration of Study: This study c...
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Army Medical College Rawalpindi
2019
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oai:doaj.org-article:2dabfebb0cc24c4991d4c5f917c87c362021-11-11T05:28:37ZFREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES0030-96482411-8842https://doaj.org/article/2dabfebb0cc24c4991d4c5f917c87c362019-08-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3222/2330https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients. Study Design: Prospective, cross-sectional analytical study. Place and Duration of Study: This study conducted in the emergency department of Punjab Institute of cardiology, Lahore Pakistan, from Mar 2017 to Jun 2018. Patients and Methods: Patients with advanced 2nd degree and 3rd degree AV blocks, diagnosed on a 12-lead electrocardiogram (ECG), and no ischemic changes on the ECG were included. hs-TnT levels were done for all patients. All patients filled a preformed questionnaire. Data were entered and analyzed using IBM-SPSS-23. Results: Of the 138 patients recruited, 60.9% were male patients. The mean age of the study participants was 63.13 ± 14.73 years. Syncope was the most common presentation (78.3%). hs-TnT levels were elevated in 55.8% participants. Elevated Trop T levels were more common in male patients (63.6%). Elevated Trop T levels were significantly associated with co-morbidities including diabetes, hypertension, and smoking, and clinical presence of chest pain and syncope (p>0.05). Conclusion: Patients with non-ischemic high-grade AV blocks present with syncope. Even in absence of ischemia, troponin levels were seen in many participants. Elevated Trop T levels cannot be considered pathognomonic for myocardial ischemia.Hafiz Abdul ManaanAbdul SattarImran SaleemShamila AfshanArmy Medical College Rawalpindiarticleatrioventricular blockhigh-grade heart blockelevated troponin tMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 901-904 (2019) |
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atrioventricular block high-grade heart block elevated troponin t Medicine R Medicine (General) R5-920 |
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atrioventricular block high-grade heart block elevated troponin t Medicine R Medicine (General) R5-920 Hafiz Abdul Manaan Abdul Sattar Imran Saleem Shamila Afshan FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES |
description |
Objective: To assess the frequency of raised hs-TnT levels in patients with non-ischemic high-grade atrioventricular (AV) blocks and also to assess the cardiac risk factors in these patients.
Study Design: Prospective, cross-sectional analytical study.
Place and Duration of Study: This study conducted in the emergency department of Punjab Institute of cardiology, Lahore Pakistan, from Mar 2017 to Jun 2018.
Patients and Methods: Patients with advanced 2nd degree and 3rd degree AV blocks, diagnosed on a 12-lead electrocardiogram (ECG), and no ischemic changes on the ECG were included. hs-TnT levels were done for all patients. All patients filled a preformed questionnaire. Data were entered and analyzed using IBM-SPSS-23.
Results: Of the 138 patients recruited, 60.9% were male patients. The mean age of the study participants was 63.13 ± 14.73 years. Syncope was the most common presentation (78.3%). hs-TnT levels were elevated in 55.8% participants. Elevated Trop T levels were more common in male patients (63.6%). Elevated Trop T levels were significantly associated with co-morbidities including diabetes, hypertension, and smoking, and clinical presence of chest pain and syncope (p>0.05).
Conclusion: Patients with non-ischemic high-grade AV blocks present with syncope. Even in absence of ischemia, troponin levels were seen in many participants. Elevated Trop T levels cannot be considered pathognomonic for myocardial ischemia. |
format |
article |
author |
Hafiz Abdul Manaan Abdul Sattar Imran Saleem Shamila Afshan |
author_facet |
Hafiz Abdul Manaan Abdul Sattar Imran Saleem Shamila Afshan |
author_sort |
Hafiz Abdul Manaan |
title |
FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES |
title_short |
FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES |
title_full |
FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES |
title_fullStr |
FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES |
title_full_unstemmed |
FREQUENCY OF ELEVATED HIGH-SENSITIVITY TROPONIN T AND ASSOCIATED CARDIAC PREDICTORS IN HIGH-GRADE ATRIOVENTRICULAR BLOCK PATIENTS WITH NON-ISCHEMIC ECG CHANGES |
title_sort |
frequency of elevated high-sensitivity troponin t and associated cardiac predictors in high-grade atrioventricular block patients with non-ischemic ecg changes |
publisher |
Army Medical College Rawalpindi |
publishDate |
2019 |
url |
https://doaj.org/article/2dabfebb0cc24c4991d4c5f917c87c36 |
work_keys_str_mv |
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