A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.

There is a large burden of norovirus disease in child-care centers in Australia and around the world. Despite the ubiquity of norovirus outbreaks in child-care centers, little is known about the extent of this burden within the child-care center and the surrounding household clusters. Therefore, we...

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Autores principales:	Nicolas Roydon Smoll, Arifuzzman Khan, Jacina Walker, Jamie McMahon, Michael Kirk, Gulam Khandaker
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2daf289f71ea48f882426fecd016707c
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spelling	oai:doaj.org-article:2daf289f71ea48f882426fecd016707c2021-12-02T20:04:33ZA norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.1932-620310.1371/journal.pone.0259145https://doaj.org/article/2daf289f71ea48f882426fecd016707c2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0259145https://doaj.org/toc/1932-6203There is a large burden of norovirus disease in child-care centers in Australia and around the world. Despite the ubiquity of norovirus outbreaks in child-care centers, little is known about the extent of this burden within the child-care center and the surrounding household clusters. Therefore, we performed an in-depth analysis of a gastroenteritis outbreak to examine the patterns of transmissions, household attack rates and the basic reproduction number (R0) for Norovirus in a child-care facility. We used data from parental interviews of suspected cases sent home with gastroenteritis at a child-care center between 24th of August and 18th of September 2020. A total of 52 persons in 19 household clusters were symptomatic in this outbreak investigation. Of all transmissions, 23 (46.9%) occurred in the child-care center, the rest occurring in households. We found a household attack rate of 36.5% (95% CI 27.3, 47.1%). Serial intervals were estimated as mean 2.5 ± SD1.45 days. The R0, using time-dependent methods during the growth phase of the outbreak (days 2 to 8) was 2.4 (95% CI 1.50, 3.50). The count of affected persons of a child-care center norovirus outbreak is approximately double the count of the total symptomatic staff and attending children. In the study setting, each symptomatic child-care attendee likely infected one other child-care attendee or staff and just over one household contact on average.Nicolas Roydon SmollArifuzzman KhanJacina WalkerJamie McMahonMichael KirkGulam KhandakerPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0259145 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Nicolas Roydon Smoll Arifuzzman Khan Jacina Walker Jamie McMahon Michael Kirk Gulam Khandaker A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.
description	There is a large burden of norovirus disease in child-care centers in Australia and around the world. Despite the ubiquity of norovirus outbreaks in child-care centers, little is known about the extent of this burden within the child-care center and the surrounding household clusters. Therefore, we performed an in-depth analysis of a gastroenteritis outbreak to examine the patterns of transmissions, household attack rates and the basic reproduction number (R0) for Norovirus in a child-care facility. We used data from parental interviews of suspected cases sent home with gastroenteritis at a child-care center between 24th of August and 18th of September 2020. A total of 52 persons in 19 household clusters were symptomatic in this outbreak investigation. Of all transmissions, 23 (46.9%) occurred in the child-care center, the rest occurring in households. We found a household attack rate of 36.5% (95% CI 27.3, 47.1%). Serial intervals were estimated as mean 2.5 ± SD1.45 days. The R0, using time-dependent methods during the growth phase of the outbreak (days 2 to 8) was 2.4 (95% CI 1.50, 3.50). The count of affected persons of a child-care center norovirus outbreak is approximately double the count of the total symptomatic staff and attending children. In the study setting, each symptomatic child-care attendee likely infected one other child-care attendee or staff and just over one household contact on average.
format	article
author	Nicolas Roydon Smoll Arifuzzman Khan Jacina Walker Jamie McMahon Michael Kirk Gulam Khandaker
author_facet	Nicolas Roydon Smoll Arifuzzman Khan Jacina Walker Jamie McMahon Michael Kirk Gulam Khandaker
author_sort	Nicolas Roydon Smoll
title	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.
title_short	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.
title_full	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.
title_fullStr	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.
title_full_unstemmed	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.
title_sort	norovirus gastroenteritis outbreak in an australian child-care center: a household-level analysis.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/2daf289f71ea48f882426fecd016707c
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A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis.

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