A functional motif of long noncoding RNA Nron against osteoporosis
LncRNAs are implicated in the pathogenesis of a number of diseases. Here, the authors show that the lncRNA Nron suppresses bone resorption, and show that delivery of a functional motif of Nron increases bone mass in mouse models of osteoporosis.
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Nature Portfolio
2021
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oai:doaj.org-article:2db4d2d2e3084d188c632108a8a430b02021-12-02T15:02:55ZA functional motif of long noncoding RNA Nron against osteoporosis10.1038/s41467-021-23642-72041-1723https://doaj.org/article/2db4d2d2e3084d188c632108a8a430b02021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23642-7https://doaj.org/toc/2041-1723LncRNAs are implicated in the pathogenesis of a number of diseases. Here, the authors show that the lncRNA Nron suppresses bone resorption, and show that delivery of a functional motif of Nron increases bone mass in mouse models of osteoporosis.Fujun JinJunhui LiYong-Biao ZhangXiangning LiuMingxiang CaiMeijing LiuMengyao LiCui MaRui YueYexuan ZhuRenfa LaiZuolin WangXunming JiHuawei WeiJun DongZhiduo LiuYifei WangYao SunXiaogang WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
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DOAJ |
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EN |
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Science Q |
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Science Q Fujun Jin Junhui Li Yong-Biao Zhang Xiangning Liu Mingxiang Cai Meijing Liu Mengyao Li Cui Ma Rui Yue Yexuan Zhu Renfa Lai Zuolin Wang Xunming Ji Huawei Wei Jun Dong Zhiduo Liu Yifei Wang Yao Sun Xiaogang Wang A functional motif of long noncoding RNA Nron against osteoporosis |
| description |
LncRNAs are implicated in the pathogenesis of a number of diseases. Here, the authors show that the lncRNA Nron suppresses bone resorption, and show that delivery of a functional motif of Nron increases bone mass in mouse models of osteoporosis. |
| format |
article |
| author |
Fujun Jin Junhui Li Yong-Biao Zhang Xiangning Liu Mingxiang Cai Meijing Liu Mengyao Li Cui Ma Rui Yue Yexuan Zhu Renfa Lai Zuolin Wang Xunming Ji Huawei Wei Jun Dong Zhiduo Liu Yifei Wang Yao Sun Xiaogang Wang |
| author_facet |
Fujun Jin Junhui Li Yong-Biao Zhang Xiangning Liu Mingxiang Cai Meijing Liu Mengyao Li Cui Ma Rui Yue Yexuan Zhu Renfa Lai Zuolin Wang Xunming Ji Huawei Wei Jun Dong Zhiduo Liu Yifei Wang Yao Sun Xiaogang Wang |
| author_sort |
Fujun Jin |
| title |
A functional motif of long noncoding RNA Nron against osteoporosis |
| title_short |
A functional motif of long noncoding RNA Nron against osteoporosis |
| title_full |
A functional motif of long noncoding RNA Nron against osteoporosis |
| title_fullStr |
A functional motif of long noncoding RNA Nron against osteoporosis |
| title_full_unstemmed |
A functional motif of long noncoding RNA Nron against osteoporosis |
| title_sort |
functional motif of long noncoding rna nron against osteoporosis |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/2db4d2d2e3084d188c632108a8a430b0 |
| work_keys_str_mv |
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