F-actin mechanics control spindle centring in the mouse zygote

How the mitotic spindle is positioned in the centre of the cell during the first mitotic division is not clear. Here Chaigne et al.show that the pronucleus coarsely centres using F-actin/Myosin-Vb dynamics, and the metaphase plate is finely centred by an F-actin cage influenced by high cortical tens...

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Autores principales:	Agathe Chaigne, Clément Campillo, Raphaël Voituriez, Nir S. Gov, Cécile Sykes, Marie-Hélène Verlhac, Marie-Emilie Terret
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2db63ef515514eb3964e8307e1af04d8
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id	oai:doaj.org-article:2db63ef515514eb3964e8307e1af04d8
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spelling	oai:doaj.org-article:2db63ef515514eb3964e8307e1af04d82021-12-02T17:33:21ZF-actin mechanics control spindle centring in the mouse zygote10.1038/ncomms102532041-1723https://doaj.org/article/2db63ef515514eb3964e8307e1af04d82016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10253https://doaj.org/toc/2041-1723How the mitotic spindle is positioned in the centre of the cell during the first mitotic division is not clear. Here Chaigne et al.show that the pronucleus coarsely centres using F-actin/Myosin-Vb dynamics, and the metaphase plate is finely centred by an F-actin cage influenced by high cortical tension.Agathe ChaigneClément CampilloRaphaël VoituriezNir S. GovCécile SykesMarie-Hélène VerlhacMarie-Emilie TerretNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Agathe Chaigne Clément Campillo Raphaël Voituriez Nir S. Gov Cécile Sykes Marie-Hélène Verlhac Marie-Emilie Terret F-actin mechanics control spindle centring in the mouse zygote
description	How the mitotic spindle is positioned in the centre of the cell during the first mitotic division is not clear. Here Chaigne et al.show that the pronucleus coarsely centres using F-actin/Myosin-Vb dynamics, and the metaphase plate is finely centred by an F-actin cage influenced by high cortical tension.
format	article
author	Agathe Chaigne Clément Campillo Raphaël Voituriez Nir S. Gov Cécile Sykes Marie-Hélène Verlhac Marie-Emilie Terret
author_facet	Agathe Chaigne Clément Campillo Raphaël Voituriez Nir S. Gov Cécile Sykes Marie-Hélène Verlhac Marie-Emilie Terret
author_sort	Agathe Chaigne
title	F-actin mechanics control spindle centring in the mouse zygote
title_short	F-actin mechanics control spindle centring in the mouse zygote
title_full	F-actin mechanics control spindle centring in the mouse zygote
title_fullStr	F-actin mechanics control spindle centring in the mouse zygote
title_full_unstemmed	F-actin mechanics control spindle centring in the mouse zygote
title_sort	f-actin mechanics control spindle centring in the mouse zygote
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2db63ef515514eb3964e8307e1af04d8
work_keys_str_mv	AT agathechaigne factinmechanicscontrolspindlecentringinthemousezygote AT clementcampillo factinmechanicscontrolspindlecentringinthemousezygote AT raphaelvoituriez factinmechanicscontrolspindlecentringinthemousezygote AT nirsgov factinmechanicscontrolspindlecentringinthemousezygote AT cecilesykes factinmechanicscontrolspindlecentringinthemousezygote AT marieheleneverlhac factinmechanicscontrolspindlecentringinthemousezygote AT marieemilieterret factinmechanicscontrolspindlecentringinthemousezygote
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F-actin mechanics control spindle centring in the mouse zygote

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