The formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles
We studied the response of trigger systems in healthy volunteers living in areas with different levels of air pollution. We determined that particles with the size of 800 microns and higher of relatively favorable region, particles with the size of less than 50 microns dominated in the air of the un...
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Scientific Сentre for Family Health and Human Reproduction Problems
2016
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oai:doaj.org-article:2dc257935aba4d399404122f3a06ff102021-11-23T06:14:34ZThe formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles2541-94202587-959610.12737/article_590823a47defa8.34126398https://doaj.org/article/2dc257935aba4d399404122f3a06ff102016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/193https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596We studied the response of trigger systems in healthy volunteers living in areas with different levels of air pollution. We determined that particles with the size of 800 microns and higher of relatively favorable region, particles with the size of less than 50 microns dominated in the air of the unfavorable area, among which there were the most hazardous to health amounts of microparticles - from 200 to 300 nm. Microparticles of unfavorable area causes the development of oxidative modifications of proteins and DNA contributing to the change of leukocyte potential energy. The increase in total antioxidant activity and response of thiol-disulfide system (the increase in thioredoxin, glutathione with a stable reductase level] maintains a balance of oxidation and antioxidant processes contributing to protection of the cellular and subcellular structures against considerable oxidative damage.T. I. VitkinaV. I. YankovaT. A. GvozdenkoY. K. DenisenkoK. S. GolokhvastScientific Сentre for Family Health and Human Reproduction Problemsarticlemicroparticles of atmospheric airhealthy people of the urbanized territoryoxidative stressthiol-disulfide systemScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(2), Pp 82-85 (2016) |
| institution |
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| collection |
DOAJ |
| language |
RU |
| topic |
microparticles of atmospheric air healthy people of the urbanized territory oxidative stress thiol-disulfide system Science Q |
| spellingShingle |
microparticles of atmospheric air healthy people of the urbanized territory oxidative stress thiol-disulfide system Science Q T. I. Vitkina V. I. Yankova T. A. Gvozdenko Y. K. Denisenko K. S. Golokhvast The formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles |
| description |
We studied the response of trigger systems in healthy volunteers living in areas with different levels of air pollution. We determined that particles with the size of 800 microns and higher of relatively favorable region, particles with the size of less than 50 microns dominated in the air of the unfavorable area, among which there were the most hazardous to health amounts of microparticles - from 200 to 300 nm. Microparticles of unfavorable area causes the development of oxidative modifications of proteins and DNA contributing to the change of leukocyte potential energy. The increase in total antioxidant activity and response of thiol-disulfide system (the increase in thioredoxin, glutathione with a stable reductase level] maintains a balance of oxidation and antioxidant processes contributing to protection of the cellular and subcellular structures against considerable oxidative damage. |
| format |
article |
| author |
T. I. Vitkina V. I. Yankova T. A. Gvozdenko Y. K. Denisenko K. S. Golokhvast |
| author_facet |
T. I. Vitkina V. I. Yankova T. A. Gvozdenko Y. K. Denisenko K. S. Golokhvast |
| author_sort |
T. I. Vitkina |
| title |
The formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles |
| title_short |
The formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles |
| title_full |
The formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles |
| title_fullStr |
The formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles |
| title_full_unstemmed |
The formation of oxidative disorders in the population of Vladivostok under the influence of atmospheric microparticles |
| title_sort |
formation of oxidative disorders in the population of vladivostok under the influence of atmospheric microparticles |
| publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
| publishDate |
2016 |
| url |
https://doaj.org/article/2dc257935aba4d399404122f3a06ff10 |
| work_keys_str_mv |
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| _version_ |
1718417060033200128 |