Detecting topological variations of DNA at single-molecule level

Ultrathin nanopore membranes have the potential for detecting topological variation in DNA. Here the authors use barcoded DNA to characterise the translocation profiles of DNA with single strand gaps.

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Autores principales:	Ke Liu, Chao Pan, Alexandre Kuhn, Adrian Pascal Nievergelt, Georg E. Fantner, Olgica Milenkovic, Aleksandra Radenovic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2dcd29896ff9406abe890ac4b7a9db77
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spelling	oai:doaj.org-article:2dcd29896ff9406abe890ac4b7a9db772021-12-02T17:02:02ZDetecting topological variations of DNA at single-molecule level10.1038/s41467-018-07924-12041-1723https://doaj.org/article/2dcd29896ff9406abe890ac4b7a9db772019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07924-1https://doaj.org/toc/2041-1723Ultrathin nanopore membranes have the potential for detecting topological variation in DNA. Here the authors use barcoded DNA to characterise the translocation profiles of DNA with single strand gaps.Ke LiuChao PanAlexandre KuhnAdrian Pascal NievergeltGeorg E. FantnerOlgica MilenkovicAleksandra RadenovicNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ke Liu Chao Pan Alexandre Kuhn Adrian Pascal Nievergelt Georg E. Fantner Olgica Milenkovic Aleksandra Radenovic Detecting topological variations of DNA at single-molecule level
description	Ultrathin nanopore membranes have the potential for detecting topological variation in DNA. Here the authors use barcoded DNA to characterise the translocation profiles of DNA with single strand gaps.
format	article
author	Ke Liu Chao Pan Alexandre Kuhn Adrian Pascal Nievergelt Georg E. Fantner Olgica Milenkovic Aleksandra Radenovic
author_facet	Ke Liu Chao Pan Alexandre Kuhn Adrian Pascal Nievergelt Georg E. Fantner Olgica Milenkovic Aleksandra Radenovic
author_sort	Ke Liu
title	Detecting topological variations of DNA at single-molecule level
title_short	Detecting topological variations of DNA at single-molecule level
title_full	Detecting topological variations of DNA at single-molecule level
title_fullStr	Detecting topological variations of DNA at single-molecule level
title_full_unstemmed	Detecting topological variations of DNA at single-molecule level
title_sort	detecting topological variations of dna at single-molecule level
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2dcd29896ff9406abe890ac4b7a9db77
work_keys_str_mv	AT keliu detectingtopologicalvariationsofdnaatsinglemoleculelevel AT chaopan detectingtopologicalvariationsofdnaatsinglemoleculelevel AT alexandrekuhn detectingtopologicalvariationsofdnaatsinglemoleculelevel AT adrianpascalnievergelt detectingtopologicalvariationsofdnaatsinglemoleculelevel AT georgefantner detectingtopologicalvariationsofdnaatsinglemoleculelevel AT olgicamilenkovic detectingtopologicalvariationsofdnaatsinglemoleculelevel AT aleksandraradenovic detectingtopologicalvariationsofdnaatsinglemoleculelevel
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Detecting topological variations of DNA at single-molecule level

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