Formulating a functional drink with antiosteoporosis effects

Introduction. Osteoporosis is one of the most common diseases of the musculoskeletal system in modern clinical practice. Its prevention and treatment requires a diet with a sufficient intake of calcium, vitamins, and connective tissue proteins that regenerate cartilage and bone tissue. We aimed to f...

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Autores principales:	Marietta A. Aslanova, Anastasia A. Semenova, Olga K. Derevitskaya
Formato:	article
Lenguaje:	EN
Publicado:	Kemerovo State University 2021
Materias:	collagen fermentolysate osteoporosis functional foods raw meat calcium oophorectomy Food processing and manufacture TP368-456
Acceso en línea:	https://doaj.org/article/2dd281c5f3ee49afbae614a2c794f5be
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spelling	oai:doaj.org-article:2dd281c5f3ee49afbae614a2c794f5be2021-11-19T04:02:56ZFormulating a functional drink with antiosteoporosis effects2308-40572310-959910.21603/2308-4057-2021-2-354-363https://doaj.org/article/2dd281c5f3ee49afbae614a2c794f5be2021-11-01T00:00:00Zhttp://jfrm.ru/en/issues/1879/1947/https://doaj.org/toc/2308-4057https://doaj.org/toc/2310-9599Introduction. Osteoporosis is one of the most common diseases of the musculoskeletal system in modern clinical practice. Its prevention and treatment requires a diet with a sufficient intake of calcium, vitamins, and connective tissue proteins that regenerate cartilage and bone tissue. We aimed to formulate a functional product based on collagen fermentolysate to prevent osteoporosis and prove its effects in experiments on laboratory rats. Study objects and methods. Our study objects were collagen fermentolysate obtained from pork ears and legs (1:1) and the functional product based on it. The biological experiment was carried out on Wistar female rats exposed to osteoporosis through complete ovariectomy. Their femurs were analyzed for the contents of phosphorus, magnesium, and calcium, as well as cytometric and biochemical blood parameters. Results and discussion. The formulated functional product based on collagen fermentolysate contained 41% of the most easily assimilable peptide fractions with a low molecular weight of 10 to 20 kDa. Other components included pumpkin powder, dietary fiber, calcium, chondroprotectors, and vitamins E, C, and D3. Compared to the control, the experimental rats that received the functional product had increased contents of calcium and magnesium in the bone tissue (by 25.0 and 3.0%, respectively), a decreased content of phosphorus (by 7.0%), a calcium-to-phosphorus ratio restored to 2.4:1.0, and a higher concentration of osteocalcin in the blood serum (by 15%). Conclusion. The developed functional product based on collagen fermentolysate can be used as an additional source of connective tissue protein, calcium, vitamins C, E, and D3, dietary fiber, and chondroprotectors to prevent osteoporosis.Marietta A. AslanovaAnastasia A. SemenovaOlga K. DerevitskayaKemerovo State Universityarticlecollagenfermentolysateosteoporosisfunctional foodsraw meatcalciumoophorectomyFood processing and manufactureTP368-456ENFoods and Raw Materials, Vol 9, Iss 2, Pp 354-363 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	collagen fermentolysate osteoporosis functional foods raw meat calcium oophorectomy Food processing and manufacture TP368-456
spellingShingle	collagen fermentolysate osteoporosis functional foods raw meat calcium oophorectomy Food processing and manufacture TP368-456 Marietta A. Aslanova Anastasia A. Semenova Olga K. Derevitskaya Formulating a functional drink with antiosteoporosis effects
description	Introduction. Osteoporosis is one of the most common diseases of the musculoskeletal system in modern clinical practice. Its prevention and treatment requires a diet with a sufficient intake of calcium, vitamins, and connective tissue proteins that regenerate cartilage and bone tissue. We aimed to formulate a functional product based on collagen fermentolysate to prevent osteoporosis and prove its effects in experiments on laboratory rats. Study objects and methods. Our study objects were collagen fermentolysate obtained from pork ears and legs (1:1) and the functional product based on it. The biological experiment was carried out on Wistar female rats exposed to osteoporosis through complete ovariectomy. Their femurs were analyzed for the contents of phosphorus, magnesium, and calcium, as well as cytometric and biochemical blood parameters. Results and discussion. The formulated functional product based on collagen fermentolysate contained 41% of the most easily assimilable peptide fractions with a low molecular weight of 10 to 20 kDa. Other components included pumpkin powder, dietary fiber, calcium, chondroprotectors, and vitamins E, C, and D3. Compared to the control, the experimental rats that received the functional product had increased contents of calcium and magnesium in the bone tissue (by 25.0 and 3.0%, respectively), a decreased content of phosphorus (by 7.0%), a calcium-to-phosphorus ratio restored to 2.4:1.0, and a higher concentration of osteocalcin in the blood serum (by 15%). Conclusion. The developed functional product based on collagen fermentolysate can be used as an additional source of connective tissue protein, calcium, vitamins C, E, and D3, dietary fiber, and chondroprotectors to prevent osteoporosis.
format	article
author	Marietta A. Aslanova Anastasia A. Semenova Olga K. Derevitskaya
author_facet	Marietta A. Aslanova Anastasia A. Semenova Olga K. Derevitskaya
author_sort	Marietta A. Aslanova
title	Formulating a functional drink with antiosteoporosis effects
title_short	Formulating a functional drink with antiosteoporosis effects
title_full	Formulating a functional drink with antiosteoporosis effects
title_fullStr	Formulating a functional drink with antiosteoporosis effects
title_full_unstemmed	Formulating a functional drink with antiosteoporosis effects
title_sort	formulating a functional drink with antiosteoporosis effects
publisher	Kemerovo State University
publishDate	2021
url	https://doaj.org/article/2dd281c5f3ee49afbae614a2c794f5be
work_keys_str_mv	AT mariettaaaslanova formulatingafunctionaldrinkwithantiosteoporosiseffects AT anastasiaasemenova formulatingafunctionaldrinkwithantiosteoporosiseffects AT olgakderevitskaya formulatingafunctionaldrinkwithantiosteoporosiseffects
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Formulating a functional drink with antiosteoporosis effects

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