OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2

Abstract. Flow cytometry allows estimating quantitative and qualitative structure of populations and subpopulations of immune system cells by using various methodical approaches and a wide spectrum of reagents. For diagnostics the Acquired Immune Deficiency Syndrome (AIDS) caused by a Human Immunode...

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Autores principales: S. V. Khaidukov, A. V. Zurochka
Formato: article
Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2014
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hiv
tcr
Acceso en línea:https://doaj.org/article/2dd290dd4399477187747f83e8c10aae
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spelling oai:doaj.org-article:2dd290dd4399477187747f83e8c10aae2021-11-22T07:09:45ZOPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 22220-76192313-739810.15789/2220-7619-2011-2-113-120https://doaj.org/article/2dd290dd4399477187747f83e8c10aae2014-06-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/35https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. Flow cytometry allows estimating quantitative and qualitative structure of populations and subpopulations of immune system cells by using various methodical approaches and a wide spectrum of reagents. For diagnostics the Acquired Immune Deficiency Syndrome (AIDS) caused by a Human Immunodeficiency Virus (HIV) the flow cytometry became irreplaceable. Traditionally, immunologists examine standard model of an estimation of immune dysfunction on the basis of classical markers of Т-cells (CD3, CD4, CD8) at the HIV-infection. But researchers pay less attention to other populations and subpopulations of lymphocytes, such as γδ-, αβ- and CD38+ Т-cells. The quantitative estimation of these parameters from a HIV and AIDS patients enables to see pathogenesis a HIV infection and the prediction of its development from another side.S. V. KhaidukovA. V. ZurochkaSankt-Peterburg : NIIÈM imeni Pasteraarticleflow cytometryaidscd38hivtcrγδ-t-cellsαβ-t-cellsInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 1, Iss 2, Pp 113-120 (2014)
institution DOAJ
collection DOAJ
language RU
topic flow cytometry
aids
cd38
hiv
tcr
γδ-t-cells
αβ-t-cells
Infectious and parasitic diseases
RC109-216
spellingShingle flow cytometry
aids
cd38
hiv
tcr
γδ-t-cells
αβ-t-cells
Infectious and parasitic diseases
RC109-216
S. V. Khaidukov
A. V. Zurochka
OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2
description Abstract. Flow cytometry allows estimating quantitative and qualitative structure of populations and subpopulations of immune system cells by using various methodical approaches and a wide spectrum of reagents. For diagnostics the Acquired Immune Deficiency Syndrome (AIDS) caused by a Human Immunodeficiency Virus (HIV) the flow cytometry became irreplaceable. Traditionally, immunologists examine standard model of an estimation of immune dysfunction on the basis of classical markers of Т-cells (CD3, CD4, CD8) at the HIV-infection. But researchers pay less attention to other populations and subpopulations of lymphocytes, such as γδ-, αβ- and CD38+ Т-cells. The quantitative estimation of these parameters from a HIV and AIDS patients enables to see pathogenesis a HIV infection and the prediction of its development from another side.
format article
author S. V. Khaidukov
A. V. Zurochka
author_facet S. V. Khaidukov
A. V. Zurochka
author_sort S. V. Khaidukov
title OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2
title_short OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2
title_full OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2
title_fullStr OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2
title_full_unstemmed OPPORTUNITIES OF FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 2
title_sort opportunities of flow cytometry in diagnostics of infectious diseases. part 2
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2014
url https://doaj.org/article/2dd290dd4399477187747f83e8c10aae
work_keys_str_mv AT svkhaidukov opportunitiesofflowcytometryindiagnosticsofinfectiousdiseasespart2
AT avzurochka opportunitiesofflowcytometryindiagnosticsofinfectiousdiseasespart2
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