Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

Given the suboptimal outcome of VRC01 antibody-mediated prevention of HIV-1 infection in its first field trial, means to improve diverse antiviral activities in vivo

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Autores principales:	Benjamin S. Goldberg, Chengzi I. Kaku, Jérémy Dufloo, Timothée Bruel, Olivier Schwartz, David A. Spencer, Ann J. Hessell, Margaret E. Ackerman
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/2dd32301729747d99f4ba9482f576cd2
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spelling	oai:doaj.org-article:2dd32301729747d99f4ba9482f576cd22021-11-03T21:52:35ZRevisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity2150-751110.1128/mBio.01743-21https://doaj.org/article/2dd32301729747d99f4ba9482f576cd22021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01743-21https://doaj.org/toc/2150-7511 Given the suboptimal outcome of VRC01 antibody-mediated prevention of HIV-1 infection in its first field trial, means to improve diverse antiviral activities in vivoBenjamin S. GoldbergChengzi I. KakuJérémy DuflooTimothée BruelOlivier SchwartzDavid A. SpencerAnn J. HessellMargaret E. AckermanAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Benjamin S. Goldberg Chengzi I. Kaku Jérémy Dufloo Timothée Bruel Olivier Schwartz David A. Spencer Ann J. Hessell Margaret E. Ackerman Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity
description	Given the suboptimal outcome of VRC01 antibody-mediated prevention of HIV-1 infection in its first field trial, means to improve diverse antiviral activities in vivo
format	article
author	Benjamin S. Goldberg Chengzi I. Kaku Jérémy Dufloo Timothée Bruel Olivier Schwartz David A. Spencer Ann J. Hessell Margaret E. Ackerman
author_facet	Benjamin S. Goldberg Chengzi I. Kaku Jérémy Dufloo Timothée Bruel Olivier Schwartz David A. Spencer Ann J. Hessell Margaret E. Ackerman
author_sort	Benjamin S. Goldberg
title	Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity
title_short	Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity
title_full	Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity
title_fullStr	Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity
title_full_unstemmed	Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity
title_sort	revisiting an igg fc loss-of-function experiment: the role of complement in hiv broadly neutralizing antibody b12 activity
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/2dd32301729747d99f4ba9482f576cd2
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Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

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