Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

The authors present an extensive profile of host transcriptional respones to a diverse group of pathogens and allergens. In doing so, they identify TH1, type I IFN, TH17, and TH2 responses, that underlie each immune response in both the blood and lung, which represents a global profile of host-patho...

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Autores principales:	Akul Singhania, Christine M. Graham, Leona Gabryšová, Lúcia Moreira-Teixeira, Evangelos Stavropoulos, Jonathan M. Pitt, Probir Chakravarty, Annika Warnatsch, William J. Branchett, Laura Conejero, Jing-Wen Lin, Sophia Davidson, Mark S. Wilson, Gregory Bancroft, Jean Langhorne, Eva Frickel, Abdul K. Sesay, Simon L. Priestnall, Eleanor Herbert, Marianna Ioannou, Qian Wang, Ian R. Humphreys, Jonathan Dodd, Peter J. M. Openshaw, Katrin D. Mayer-Barber, Dragana Jankovic, Alan Sher, Clare M. Lloyd, Nicole Baldwin, Damien Chaussabel, Venizelos Papayannopoulos, Andreas Wack, Jacques F. Banchereau, Virginia M. Pascual, Anne O’Garra
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2de9148c41624ebdb261719be7a52d90
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spelling	oai:doaj.org-article:2de9148c41624ebdb261719be7a52d902021-12-02T16:57:40ZTranscriptional profiling unveils type I and II interferon networks in blood and tissues across diseases10.1038/s41467-019-10601-62041-1723https://doaj.org/article/2de9148c41624ebdb261719be7a52d902019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10601-6https://doaj.org/toc/2041-1723The authors present an extensive profile of host transcriptional respones to a diverse group of pathogens and allergens. In doing so, they identify TH1, type I IFN, TH17, and TH2 responses, that underlie each immune response in both the blood and lung, which represents a global profile of host-pathogen immune responses.Akul SinghaniaChristine M. GrahamLeona GabryšováLúcia Moreira-TeixeiraEvangelos StavropoulosJonathan M. PittProbir ChakravartyAnnika WarnatschWilliam J. BranchettLaura ConejeroJing-Wen LinSophia DavidsonMark S. WilsonGregory BancroftJean LanghorneEva FrickelAbdul K. SesaySimon L. PriestnallEleanor HerbertMarianna IoannouQian WangIan R. HumphreysJonathan DoddPeter J. M. OpenshawKatrin D. Mayer-BarberDragana JankovicAlan SherClare M. LloydNicole BaldwinDamien ChaussabelVenizelos PapayannopoulosAndreas WackJacques F. BanchereauVirginia M. PascualAnne O’GarraNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Akul Singhania Christine M. Graham Leona Gabryšová Lúcia Moreira-Teixeira Evangelos Stavropoulos Jonathan M. Pitt Probir Chakravarty Annika Warnatsch William J. Branchett Laura Conejero Jing-Wen Lin Sophia Davidson Mark S. Wilson Gregory Bancroft Jean Langhorne Eva Frickel Abdul K. Sesay Simon L. Priestnall Eleanor Herbert Marianna Ioannou Qian Wang Ian R. Humphreys Jonathan Dodd Peter J. M. Openshaw Katrin D. Mayer-Barber Dragana Jankovic Alan Sher Clare M. Lloyd Nicole Baldwin Damien Chaussabel Venizelos Papayannopoulos Andreas Wack Jacques F. Banchereau Virginia M. Pascual Anne O’Garra Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
description	The authors present an extensive profile of host transcriptional respones to a diverse group of pathogens and allergens. In doing so, they identify TH1, type I IFN, TH17, and TH2 responses, that underlie each immune response in both the blood and lung, which represents a global profile of host-pathogen immune responses.
format	article
author	Akul Singhania Christine M. Graham Leona Gabryšová Lúcia Moreira-Teixeira Evangelos Stavropoulos Jonathan M. Pitt Probir Chakravarty Annika Warnatsch William J. Branchett Laura Conejero Jing-Wen Lin Sophia Davidson Mark S. Wilson Gregory Bancroft Jean Langhorne Eva Frickel Abdul K. Sesay Simon L. Priestnall Eleanor Herbert Marianna Ioannou Qian Wang Ian R. Humphreys Jonathan Dodd Peter J. M. Openshaw Katrin D. Mayer-Barber Dragana Jankovic Alan Sher Clare M. Lloyd Nicole Baldwin Damien Chaussabel Venizelos Papayannopoulos Andreas Wack Jacques F. Banchereau Virginia M. Pascual Anne O’Garra
author_facet	Akul Singhania Christine M. Graham Leona Gabryšová Lúcia Moreira-Teixeira Evangelos Stavropoulos Jonathan M. Pitt Probir Chakravarty Annika Warnatsch William J. Branchett Laura Conejero Jing-Wen Lin Sophia Davidson Mark S. Wilson Gregory Bancroft Jean Langhorne Eva Frickel Abdul K. Sesay Simon L. Priestnall Eleanor Herbert Marianna Ioannou Qian Wang Ian R. Humphreys Jonathan Dodd Peter J. M. Openshaw Katrin D. Mayer-Barber Dragana Jankovic Alan Sher Clare M. Lloyd Nicole Baldwin Damien Chaussabel Venizelos Papayannopoulos Andreas Wack Jacques F. Banchereau Virginia M. Pascual Anne O’Garra
author_sort	Akul Singhania
title	Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
title_short	Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
title_full	Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
title_fullStr	Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
title_full_unstemmed	Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
title_sort	transcriptional profiling unveils type i and ii interferon networks in blood and tissues across diseases
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2de9148c41624ebdb261719be7a52d90
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Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

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