Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats

As the most abundantly used phthalate derivative, di-(2-ethylhexyl) phthalate (DEHP) leads to reproductive disorders, especially in males. Testicular injury can be triggered when the testis is exposed to DEHP during the immature stage. However, the potential mechanism is largely unclear. In the pres...

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Autores principales: Yifan Hong, Yu Zhou, Lianju Shen, Yuexin Wei, Chunlan Long, Yan Fu, Huan Wu, Junke Wang, Yuhao Wu, Shengde Wu, Guanghui Wei
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
ROS
Acceso en línea:https://doaj.org/article/2df0e65399624ee8b6c9710c6f60b616
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