Exercise induces new cardiomyocyte generation in the adult mammalian heart

The adult mammalian heart has a limited cardiomyogenic capacity. Here the authors show that intensive exercise leads to a 4.6-fold increase in murine cardiomyocyte proliferation requiring the expression of miR-222, and that exercise induces an extended cardiomyogenic response in the murine heart aft...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ana Vujic, Carolin Lerchenmüller, Ting-Di Wu, Christelle Guillermier, Charles P. Rabolli, Emilia Gonzalez, Samuel E. Senyo, Xiaojun Liu, Jean-Luc Guerquin-Kern, Matthew L. Steinhauser, Richard T. Lee, Anthony Rosenzweig
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2df138bce0e446388382bb5c88daeae8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2df138bce0e446388382bb5c88daeae8
record_format	dspace
spelling	oai:doaj.org-article:2df138bce0e446388382bb5c88daeae82021-12-02T14:41:06ZExercise induces new cardiomyocyte generation in the adult mammalian heart10.1038/s41467-018-04083-12041-1723https://doaj.org/article/2df138bce0e446388382bb5c88daeae82018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04083-1https://doaj.org/toc/2041-1723The adult mammalian heart has a limited cardiomyogenic capacity. Here the authors show that intensive exercise leads to a 4.6-fold increase in murine cardiomyocyte proliferation requiring the expression of miR-222, and that exercise induces an extended cardiomyogenic response in the murine heart after infarction.Ana VujicCarolin LerchenmüllerTing-Di WuChristelle GuillermierCharles P. RabolliEmilia GonzalezSamuel E. SenyoXiaojun LiuJean-Luc Guerquin-KernMatthew L. SteinhauserRichard T. LeeAnthony RosenzweigNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ana Vujic Carolin Lerchenmüller Ting-Di Wu Christelle Guillermier Charles P. Rabolli Emilia Gonzalez Samuel E. Senyo Xiaojun Liu Jean-Luc Guerquin-Kern Matthew L. Steinhauser Richard T. Lee Anthony Rosenzweig Exercise induces new cardiomyocyte generation in the adult mammalian heart
description	The adult mammalian heart has a limited cardiomyogenic capacity. Here the authors show that intensive exercise leads to a 4.6-fold increase in murine cardiomyocyte proliferation requiring the expression of miR-222, and that exercise induces an extended cardiomyogenic response in the murine heart after infarction.
format	article
author	Ana Vujic Carolin Lerchenmüller Ting-Di Wu Christelle Guillermier Charles P. Rabolli Emilia Gonzalez Samuel E. Senyo Xiaojun Liu Jean-Luc Guerquin-Kern Matthew L. Steinhauser Richard T. Lee Anthony Rosenzweig
author_facet	Ana Vujic Carolin Lerchenmüller Ting-Di Wu Christelle Guillermier Charles P. Rabolli Emilia Gonzalez Samuel E. Senyo Xiaojun Liu Jean-Luc Guerquin-Kern Matthew L. Steinhauser Richard T. Lee Anthony Rosenzweig
author_sort	Ana Vujic
title	Exercise induces new cardiomyocyte generation in the adult mammalian heart
title_short	Exercise induces new cardiomyocyte generation in the adult mammalian heart
title_full	Exercise induces new cardiomyocyte generation in the adult mammalian heart
title_fullStr	Exercise induces new cardiomyocyte generation in the adult mammalian heart
title_full_unstemmed	Exercise induces new cardiomyocyte generation in the adult mammalian heart
title_sort	exercise induces new cardiomyocyte generation in the adult mammalian heart
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2df138bce0e446388382bb5c88daeae8
work_keys_str_mv	AT anavujic exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT carolinlerchenmuller exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT tingdiwu exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT christelleguillermier exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT charlesprabolli exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT emiliagonzalez exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT samuelesenyo exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT xiaojunliu exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT jeanlucguerquinkern exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT matthewlsteinhauser exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT richardtlee exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart AT anthonyrosenzweig exerciseinducesnewcardiomyocytegenerationintheadultmammalianheart
_version_	1718389981568827392

Exercise induces new cardiomyocyte generation in the adult mammalian heart

Ejemplares similares