Exercise induces new cardiomyocyte generation in the adult mammalian heart

The adult mammalian heart has a limited cardiomyogenic capacity. Here the authors show that intensive exercise leads to a 4.6-fold increase in murine cardiomyocyte proliferation requiring the expression of miR-222, and that exercise induces an extended cardiomyogenic response in the murine heart aft...

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Autores principales: Ana Vujic, Carolin Lerchenmüller, Ting-Di Wu, Christelle Guillermier, Charles P. Rabolli, Emilia Gonzalez, Samuel E. Senyo, Xiaojun Liu, Jean-Luc Guerquin-Kern, Matthew L. Steinhauser, Richard T. Lee, Anthony Rosenzweig
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2df138bce0e446388382bb5c88daeae8
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