Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre

Objectives: To analyse the pattern of cardiovascular diseases (CVDs) in COVID-19 patients admitted to tertiary cardiac care centre. Methods: We retrospectively analysed 511 adult patients admitted between July 1, 2020, and November 30, 2020, with COVID-19 infection and having either new onset or pre...

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Autores principales:	Beeresha Puttegowda, MD, DM, Arun B. Shivashankarappa, MD,DM,DNB, Suvradip Dutta, MD,(DM), Rama Chikkamuniswamy, MD,DM, Prabhavathi Bhat, MD,DM, Shanmugam Krishnan, MD,DM, Manjunath C. Nanjappa, MD, DM, FRCP, FACC, FICC
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	COVID-19 ACS STEMI NSTE-ACS Myocarditis Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/2df928d7fb1b48ff976539a83cb74153
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spelling	oai:doaj.org-article:2df928d7fb1b48ff976539a83cb741532021-12-02T04:58:01ZPatterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre0019-483210.1016/j.ihj.2021.10.007https://doaj.org/article/2df928d7fb1b48ff976539a83cb741532021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S001948322100225Xhttps://doaj.org/toc/0019-4832Objectives: To analyse the pattern of cardiovascular diseases (CVDs) in COVID-19 patients admitted to tertiary cardiac care centre. Methods: We retrospectively analysed 511 adult patients admitted between July 1, 2020, and November 30, 2020, with COVID-19 infection and having either new onset or pre-existing CVDs. Clinical features, electrocardiogram (ECG), echocardiography, chest X-ray, biomarkers, haematological and biochemical parameters were analysed. Results: The mean age of the patients was 56.62 ± 14.74 years. Male: Female ratio was 2.78:1. Pre-existing CVDs were present in 258 patients (50.5%). The most common cardiovascular manifestation was acute coronary syndrome (ACS), seen in 259 patients (50.7%). ST-segment elevation myocardial infarction (STEMI) was more common than non-ST-segment elevation ACS (NSTE-ACS). Possible myocarditis was seen in 52 patients (10.1%). Rhythm and conduction abnormalities were noted in 144 patients (28.2%), the most common being QT prolongation, seen in 51 patients (10%). In-hospital mortality occurred in 97 patients (18.9%). Age, serum Ferritin level, D-dimer, NT-pro-BNP and total leukocyte count were significantly higher among patients with in-hospital mortality compared to survival group. Blood lymphocyte count and Haemoglobin level were significantly lower in mortality-group, compared to survival-group. Incidence of pre-existing CVDs, cardiogenic shock, heart failure, atrial fibrillation (AF), and renal failure were significantly higher in mortality-group compared to survival-group. Conclusion: The most common CVD in COVID-19 patients in our study was ACS. STEMI was more common than NSTE-ACS. Advanced age, elevated serum ferritin, D-dimer, NT pro-BNP, leucocytosis, lymphopenia, lower haemoglobin, pre-existing CVDs heart failure, cardiogenic shock, AF and renal failure were associated with increased mortality in these patients.Beeresha Puttegowda, MD, DMArun B. Shivashankarappa, MD,DM,DNBSuvradip Dutta, MD,(DM)Rama Chikkamuniswamy, MD,DMPrabhavathi Bhat, MD,DMShanmugam Krishnan, MD,DMManjunath C. Nanjappa, MD, DM, FRCP, FACC, FICCElsevierarticleCOVID-19ACSSTEMINSTE-ACSMyocarditisSurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENIndian Heart Journal, Vol 73, Iss 6, Pp 682-686 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 ACS STEMI NSTE-ACS Myocarditis Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	COVID-19 ACS STEMI NSTE-ACS Myocarditis Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 Beeresha Puttegowda, MD, DM Arun B. Shivashankarappa, MD,DM,DNB Suvradip Dutta, MD,(DM) Rama Chikkamuniswamy, MD,DM Prabhavathi Bhat, MD,DM Shanmugam Krishnan, MD,DM Manjunath C. Nanjappa, MD, DM, FRCP, FACC, FICC Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre
description	Objectives: To analyse the pattern of cardiovascular diseases (CVDs) in COVID-19 patients admitted to tertiary cardiac care centre. Methods: We retrospectively analysed 511 adult patients admitted between July 1, 2020, and November 30, 2020, with COVID-19 infection and having either new onset or pre-existing CVDs. Clinical features, electrocardiogram (ECG), echocardiography, chest X-ray, biomarkers, haematological and biochemical parameters were analysed. Results: The mean age of the patients was 56.62 ± 14.74 years. Male: Female ratio was 2.78:1. Pre-existing CVDs were present in 258 patients (50.5%). The most common cardiovascular manifestation was acute coronary syndrome (ACS), seen in 259 patients (50.7%). ST-segment elevation myocardial infarction (STEMI) was more common than non-ST-segment elevation ACS (NSTE-ACS). Possible myocarditis was seen in 52 patients (10.1%). Rhythm and conduction abnormalities were noted in 144 patients (28.2%), the most common being QT prolongation, seen in 51 patients (10%). In-hospital mortality occurred in 97 patients (18.9%). Age, serum Ferritin level, D-dimer, NT-pro-BNP and total leukocyte count were significantly higher among patients with in-hospital mortality compared to survival group. Blood lymphocyte count and Haemoglobin level were significantly lower in mortality-group, compared to survival-group. Incidence of pre-existing CVDs, cardiogenic shock, heart failure, atrial fibrillation (AF), and renal failure were significantly higher in mortality-group compared to survival-group. Conclusion: The most common CVD in COVID-19 patients in our study was ACS. STEMI was more common than NSTE-ACS. Advanced age, elevated serum ferritin, D-dimer, NT pro-BNP, leucocytosis, lymphopenia, lower haemoglobin, pre-existing CVDs heart failure, cardiogenic shock, AF and renal failure were associated with increased mortality in these patients.
format	article
author	Beeresha Puttegowda, MD, DM Arun B. Shivashankarappa, MD,DM,DNB Suvradip Dutta, MD,(DM) Rama Chikkamuniswamy, MD,DM Prabhavathi Bhat, MD,DM Shanmugam Krishnan, MD,DM Manjunath C. Nanjappa, MD, DM, FRCP, FACC, FICC
author_facet	Beeresha Puttegowda, MD, DM Arun B. Shivashankarappa, MD,DM,DNB Suvradip Dutta, MD,(DM) Rama Chikkamuniswamy, MD,DM Prabhavathi Bhat, MD,DM Shanmugam Krishnan, MD,DM Manjunath C. Nanjappa, MD, DM, FRCP, FACC, FICC
author_sort	Beeresha Puttegowda, MD, DM
title	Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre
title_short	Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre
title_full	Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre
title_fullStr	Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre
title_full_unstemmed	Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre
title_sort	patterns of cardiovascular diseases in covid-19 patients admitted to tertiary cardiac care centre
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/2df928d7fb1b48ff976539a83cb74153
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Patterns of cardiovascular diseases in COVID-19 patients admitted to tertiary cardiac care centre

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