Identification of a nanobody specific to human pulmonary surfactant protein A

Identification of a nanobody specific to human pulmonary surfactant protein A

Abstract Nanobody (Nb) is a promising vector for targeted drug delivery. This study aims to identify an Nb that can specifically target the lung by binding human pulmonary surfactant protein A (SP-A). Human lung frozen tissue sections were used for 3 rounds of biospanning of our previously construct...

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Bibliographic Details
Main Authors: Xian He, Shan-Mei Wang, Zhao Fang Yin, Meng-Meng Zhao, Nan Li, Feng Yu, Liu-Sheng Wang, Yang Hu, Yu-Kui Du, Shan-Shan Du, Yan Li, Ya-Ru Wei, Shan-Shan Chen, Jian-Hua He, Dong Weng, Hui-Ping Li
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/2dfa83ef24744015bf52012dcd455845
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